Funded Projects

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Project # Project Title Research Focus Area Research Program Administering IC Institution(s) Investigator(s) Location(s) Year Awarded
1OT2DA062972-01
Increasing the Capacity of a Community-Based Research Center to Address Opioid Use Disorder and Related Health Inequities in Urban American Indian Communities Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA NATIVE AMERICAN COMMUNITY CLINIC STATELY, ANTONY Minneapolis, MN 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain (OT2)
NOFO Number: OTA-23-007
1R01DA058640-01A1
Improving Perioperative Care for Patients with Opioid Use Disorder New Strategies to Prevent and Treat Opioid Addiction NIDA UNIVERSITY OF MICHIGAN BICKET, MARK (contact); WALJEE, JENNIFER FILIP Ann Arbor, MI 2024
NOFO Title: Research Project Grant (Parent R01 Clinical Trial Required)
NOFO Number: PA-20-183
3UG1DA050072-05S1
TCN PATHS Supplemental funding Translation of Research to Practice for the Treatment of Opioid Addiction Justice Community Overdose Innovation Network (JCOIN) NIDA YALE UNIVERSITY WANG, EMILY AI-HUA New Haven, CT 2024
NOFO Title: Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
NOFO Number: PA-20-272
3R01DA057668-01S1
Enhancing Precision in Overdose Mortality Prediction through Data Linkage: A Heterogeneous Capture-Recapture Approach to Estimating Opioid Use Disorder Prevalence in Ohio Cross-Cutting Research Leveraging Existing and Real-Time Opioid and Pain Management Data NIDA OHIO STATE UNIVERSITY FERNANDEZ, SOLEDAD A (contact); FAREED, NALEEF Columbus, OH 2024
NOFO Title: Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
NOFO Number: PA-20-272
1R43DA058603-01A1
Developing a novel epigenetic regulator as a treatment for opioid use disorder Cross-Cutting Research Small Business Programs NIDA EPIVARIO, LLC KIM, THOMAS Philadelphia, PA 2024
NOFO Title: PHS 2022-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)
NOFO Number: PA-22-176
3U01DA055355-04S1
9/24- Healthy Brain and Child Development National Consortium Training the Next Generation of Researchers in HEAL NIDA NORTHWESTERN UNIVERSITY CHICAGO WAKSCHLAG, LAUREN S (contact); NORTON, ELIZABETH SPENCER Chicago, IL 2024
NOFO Title: Research Supplements to Promote Diversity in Health-Related Research (Admin Supp Clinical Trial Not Allowed)
NOFO Number: PA-23-189
4UH3DA054825-03
A novel and highly selective orexin 1 receptor antagonist for the treatment of patients with opioid use disorder. Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA ASTRAZENECA PHARMACEUTICALS, LP GURRELL, IAN Wilmington, DE 2024
NOFO Title: Development of Medications to Prevent and Treat Opioid Use Disorders and Overdose (UG3/UH3) (Clinical Trial Optional)
NOFO Number: PAR-20-092
1U01DA059994-01
Efficacy, safety, and pharmacokinetic study of BICX104 naltrexone subcutaneous implant alone and in combination with bupropion for the treatment of Methamphetamine Use Disorder (MUD). Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA BIOCORRX PHARMACEUTICALS, INC. DEVARNEY, KATE BEEBE Anaheim, CA 2024
NOFO Title: Grand Opportunity in Medications Development for Substance-Use Disorders (U01 Clinical Trial Optional)
NOFO Number: PAR-22-202
1K01DA061078-01
Reducing opioid misuse among urban Indigenous young adults in Montana using a culturally centered intervention Training the Next Generation of Researchers in HEAL NIDA UNIVERSITY OF MONTANA CHASE-BEGAY, DAMIAN M Missoula, MT 2024
NOFO Title: HEAL Initiative: Career Development Awards in Implementation Science for Substance Use Prevention and Treatment (K01 - Clinical Trial Required)
NOFO Number: PAS-22-206
4UH3DA050325-03
Use of a GLP-1 Agonist to Treat Opioid Use Disorder in Rats and Man Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA PENN STATE HEALTH HERSHEY MEDICAL CENTER GRIGSON, PATRICIA SUE (contact); BRICK, TIMOTHY R; BUNCE, SCOTT C; NYLAND, JENNIFER E Hershey, PA 2024
NOFO Title: Development of Medications to Prevent and Treat Opioid Use Disorders and Overdose (UG3/UH3) (Clinical Trials Optional)
NOFO Number: RFA-DA-19-002
4R33DA057600-02
Using data to drive action to reduce opioid overdoses in Seattle, WA Cross-Cutting Research HEAL Data2Action (HD2A) NIDA UNIVERSITY OF WASHINGTON BANTA-GREEN, CALEB (contact); HOOD, JULIA ELIZABETH Seattle, WA 2024
NOFO Title: HEAL Initiative: HEAL Data2Action Innovation Projects (R61/R33 Clinical Trial Optional)
NOFO Number: RFA-DA-22-051
1R61DA059893-01A1
Staffing and Supports for Implementing Cross-System Interventions with Peer Mentors Translation of Research to Practice for the Treatment of Opioid Addiction Optimizing the Quality, Reach, and Impact of Addiction Services NIDA OHIO STATE UNIVERSITY BUNGER, ALICIA C (contact); SALDANA, LISA Columbus, OH 2024
NOFO Title: HEAL Initiative: Translating Research to Practice to End the Overdose Crisis (R61/R33 Clinical Trial Optional)
NOFO Number: RFA-DA-23-053
1R61DA062335-01
Families left behind: Addressing prolonged grief and substance use disorders among people bereaved by drug overdose deaths Translation of Research to Practice for the Treatment of Opioid Addiction Optimizing the Quality, Reach, and Impact of Addiction Services NIDA STANFORD UNIVERSITY OSILLA, KAREN CHAN (contact); ATHEY, ALISON Standford, CA 2024
NOFO Title: HEAL Initiative: Translating Research to Practice to End the Overdose Crisis (R61/R33 Clinical Trial Optional)
NOFO Number: RFA-DA-23-053
1R24DA061190-01
PRIDE-CARES Center: Patient-Responsive Initiatives for Diverse Engagement - LGBTQ+ Community Action in Research to Eliminate Substance Use Disorder Translation of Research to Practice for the Treatment of Opioid Addiction NIDA UNIVERSITY OF SOUTH CAROLINA NATAFGI, NABIL M (contact); FIVECOAT, JAIME ERIN; KENNEDY, ANN BLAIR Columbia, SC 2024
NOFO Title: Patient Engagement Resource Centers to Inform SUD Treatment Services Research (R24 Clinical Trial Optional)
NOFO Number: RFA-DA-24-016
1R21DA061784-01
Preclinical Trial: Targeting the Neuropeptide S Receptor to Curb Opioid Taking and Seeking Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA STATE UNIVERSITY OF NEW YORK AT BUFFALO CLARK, STEWART DONALDSON Amherst, NY 2024
NOFO Title: HEAL Initiative: Novel Targets for Opioid Use Disorders and Opioid Overdose (R21 Clinical Trial Not Allowed)
NOFO Number: RFA-DA-24-064
1UG3DA062088-01
Evaluation of psilocybin as an adjunctive treatment for opioid use disorder in methadone-maintained patients who continue to use illicit opioids Novel Therapeutic Options for Opioid Use Disorder and Overdose Focusing Medication Development to Prevent and Treat Opioid Use Disorder and Overdose NIDA NEW YORK UNIVERSITY SCHOOL OF MEDICINE BOGENSCHUTZ, MICHAEL PARKS New York, NY 2024
NOFO Title: Psychedelics Treatment Research in Substance Use Disorder (UG3/UH3 Clinical Trials Optional)
NOFO Number: RFA-DA-25-058
4U01HL150568-02
Effects of experimental sleep disruption and fragmentation on cerebral Mu-opioid receptor function, Mu-opioid receptor agonist analgesia, and abuse liability New Strategies to Prevent and Treat Opioid Addiction Sleep Dysfunction as a Core Feature of Opioid Use Disorder and Recovery NHLBI JOHNS HOPKINS UNIVERSITY SMITH, MICHAEL T Baltimore, MD 2024
NOFO Title: HEAL Initiative: Sleep and Circadian-Dependent Mechanisms Contributing to Opiate Use Disorder (OUD) and Response to Medication Assisted Treatment (MAT) (U01 Clinical Trial Optional)
NOFO Number: RFA-HL-19-029
1R21DA060111-01
The potential benefits of autophagy activator TFEB in opioid use disorder in mice Novel Therapeutic Options for Opioid Use Disorder and Overdose NIDA FLORIDA INTERNATIONAL UNIVERSITY LAKSHMANA, MADEPALLI KRISHNAPPA Miami, FL 2024
NOFO Title: Emergency Awards: HEAL Initiative-Early-Stage Discovery of New Pain and Opioid Use Disorder Targets Within the Understudied Druggable Proteome (R21 Clinical Trial Not Allowed)
NOFO Number: RFA-TR-23-010
3OT2OD037643-01S1
All of Us Research Program New York Consortium New Strategies to Prevent and Treat Opioid Addiction OD ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI KRAFT, MONICA (contact); HOROWITZ, CAROL R; NADKARNI, GIRISH NITIN; SHROFF, NANDINI; SHUMAN, SASKIA New York, NY 2024
NOFO Title: All of Us Engagement, Communications, and Enrollment Partnerships
NOFO Number: OTA-22-006
1OT2DA061138-01
Commitment to Recovery: Alaska Native Community Needs for Substance Use Treatment Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA SOUTHCENTRAL FOUNDATION SHANE, ALIASSA (contact); MICHLIG, GEORGIA J; TRINIDAD, SUSAN BROWN Anchorage, AK 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain (OT2)
NOFO Number: OTA-23-007
1OT2DA061145-01
Northwest Regional Research Center Translation of Research to Practice for the Treatment of Opioid Addiction Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain NIDA NORTHWEST PORTLAND AREA INDIAN HEALTH BOARD TOWN, MATTHEW ALAN Portland, OR 2024
NOFO Title: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program - Addressing Overdose, Substance Use, Mental Health, and Pain Native Research Resource Network (OT2)
NOFO Number: OTA-23-008
1R01DA059640-01A1
Craving-based Digital Phenotyping During MOUD Treatment New Strategies to Prevent and Treat Opioid Addiction NIDA UMASS CHAN MEDICAL SCHOOL CARREIRO, STEPHANIE P Worcester, MA 2024
NOFO Title: NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)
NOFO Number: PA-20-185
3UG1DA015831-23S2
CTN145: Standard versus High Dose ED-Initiated Buprenorphine Induction Administrative Supplement 1 New Strategies to Prevent and Treat Opioid Addiction Optimizing the Quality, Reach, and Impact of Addiction Services NIDA YALE UNIVERSITY D'ONOFRIO, GAIL (contact); HAWK, KATHRYN; HERRING, ANDREW New Haven, CT 2024
NOFO Title: Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
NOFO Number: PA-20-272
3UG1DA015831-23S1
EMS initiated Buprenorphine for Opioid Use Disorder Translation of Research to Practice for the Treatment of Opioid Addiction Enhancing the National Drug Abuse Treatment Clinical Trials Network to Address Opioids NIDA YALE UNIVERSITY D'ONOFRIO, GAIL (contact); CARROLL, GERARD; HSER, YIH-ING; KEATING, ELIZABETH New Haven, CT 2024
NOFO Title: Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
NOFO Number: PA-20-272
3U01DA055363-04S1
The Transgenerational Influence of Discrimination on Mental Health Training the Next Generation of Researchers in HEAL NIDA OREGON HEALTH & SCIENCE UNIVERSITY SULLIVAN, ELINOR L (contact); GRAHAM, ALICE M Portland, OR 2024
NOFO Title: Research Supplements to Promote Diversity in Health-Related Research (Admin Supp Clinical Trial Not Allowed)
NOFO Number: PA-23-189