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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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New study uncovers how genes influence retinal aging and brain health

Researchers at the Jackson Laboratories used mice with nine different genetic backgrounds to identify factors influencing eye aging, paving the way for eye-based diagnostics for neurodegenerative diseases

NEI study: New take on old marker of cell death

New findings from a National Eye Institute-led study add a twist on how a widely used cell death marker, annexin-V, can be interpreted in the lab and the clinic for tracking retinal cell death in eye diseases such as glaucoma.

UC Irvine-co-led study finds DNA damage is key factor in age-related macular degeneration

Study reveals how DNA damage, a hallmark of aging, compromises the retina’s function and accelerates vision loss. Targeting specific retinal cell types could lead to treatments that slow or stop progression.
Image of retina

Researchers seek new treatment for blinding diseases AMD and Stargardt

Research team has identified advanced preclinical candidates targeting the bisretinoid synthesis pathway, which could help treat macular degeneration and Stargardt disease.
Fundus photograph of age-related macular degeneration showing drusen.

New research offers hope for preventing age-related blindness

New research from the University of Rochester provides important insights into the cellular mechanisms behind AMD and offers potential avenues for new treatments.
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U. Minnesota researchers discover potential new pathway to prevent age-related macular degeneration

The team identified small molecules that can reduce the production of proteins linked to age-related macular degeneration.
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NIH researchers discover potential therapeutic target for degenerative eye disease

Researchers from the National Institutes of Health (NIH) have discovered the source of dysfunction in the process whereby cells in the eye's retina remove waste.

Supplements slow disease progression during late stage of “dry” age-related macular degeneration

Researchers have found that taking a daily supplement containing antioxidant vitamins and minerals slows progression of late-stage dry age-related macular degeneration (AMD), potentially helping people preserve their central vision.
AMD simulation

A new target for treatment of one type of macular degeneration

A new study in mice hints at the promise of an eventual alternative treatment option for the “wet” version of age-related macular degeneration (AMD).
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Treating AMD with anti-VEGF biosimilars is safe and cost-effective, new research says

At a fraction of the cost, biosimilars are now proven to be as effective as original anti-VEGF medications.