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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Images of a patient eye with new TIMP3 maculopathy

NIH researchers discover new genetic eye disease

Researchers from the National Eye Institute (NEI) have identified a new disease that affects the macula, a small part of the light-sensing retina needed for sharp, central vision.
Cells of the fruit fly brain.

Buck researchers uncover intriguing connection between diet, eye health and lifespan

Researchers from the Buck Institute have demonstrated for the first time a link between diet, circadian rhythms, eye health and lifespan.

NIH study confirms benefit of supplements for slowing age-related macular degeneration

The AREDS2 formula not only reduces risk of lung cancer due to beta-carotene, but is also more effective at reducing risk of AMD progression, compared to the original formula.
Comparison of two retinal images.

Gene therapy for rare eye disease safe but lacks efficacy in early trial

A 28-patient phase 1 gene therapy clinical trial for the degenerative retinal disease Leber hereditary optic neuropathy (LHON) found no significant safety concerns; however, treatment failed to improve or slow vision loss, with even the highest dose.

Noninvasive technique collects sufficient tear fluid to look for biomarkers of health and disease

Scientists from Augusta University have fine-tuned a non-invasive and efficient way to evaluate the tear film for clues about wellness and disease.

Life after death for the human eye

Scientists have revived light-sensing neuron cells in organ donor eyes and restored communication between them as part of a series of discoveries that stand to transform brain and vision research.

Retinal cell map could advance precise therapies for blinding diseases

Researchers have identified distinct differences among the cells comprising a tissue in the retina that is vital to human visual perception. The scientists from the National Eye Institute (NEI) discovered five subpopulations of retinal pigment epithelium.

NEI researchers discover cellular events that precede neurodegenerative eye disease

Molecular and cellular changes in rod photoreceptors are detectable in a mouse model of retinal degeneration several days prior to observable morphological changes, according to researchers at the National Eye Institute.
Schematic shows blood vessel leakage on side of retina

Vision improvement is long-lasting with treatment for blinding blood vessel condition

NIH-funded study finds many patients with retinal vein occlusion have vision benefits, but require long-term monitoring and treatment

How do our eyes stay focused on what we reach for? Researchers uncover how our gaze is “anchored” in the brain

Findings offer new insights into how our movements are coordinated