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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Nanoparticle. Courtesy of Biorender.

Tiny nanoparticle could have big impact on patients receiving corneal transplants

Using nanoparticles to encapsulate eye medication decreased graft rejection while requiring fewer and smaller doses.
Views of a patio from a walking, crawling, or flying perspective, and a collection of scrambled views.

Visually navigating on foot uses unique brain region

Using vision to efficiently move through an area by foot uses a unique region of the brain’s cortex, according to a small study funded by the National Eye Institute (NEI).

Researchers discover therapeutic target to aid in glaucoma treatment

Indiana University researchers have identified a new therapeutic target that could lead to more effective treatment of glaucoma.
Fundus photograph of age-related macular degeneration showing drusen.

Discovery suggests new way to prevent common causes of vision loss

UVA Health scientists have discovered an unknown contributor to harmful blood vessel growth in the eye that could lead to new treatments for blinding macular degeneration and other common causes of vision loss.

HSC researcher discovered a potential cause for keratoconus

Researchers at the University of North Texas Health Science Center are the first to characterize extracellular vesicles in the tears of patients with keratoconus.
Synapses between neurons in thalamus and cortex.

Sparse, small, but diverse neural connections help make perception reliable, efficient

In a study from the Picower Institute at MIT, the first detailed mapping and modeling of thalamus inputs onto visual cortex neurons show brain leverages “wisdom of the crowd” to process sensory information.

Small creatures teach big lessons

In the vision field, researchers turn to a variety of small, non-mammalian animal models to help bridge gaps in our scientific knowledge.
Eye with coloboma

Zebrafish model helps explain eye development

Developed by NIH scientists, the model also sheds light on developmental eye disorders such as coloboma.
Green-stained limbal stem cells track towards center of mouse cornea.

Dry eye disease alters how the eye’s cornea heals itself after injury

Studying mice, researchers at Washington University School of Medicine in St. Louis have found that proteins made by stem cells that regenerate the cornea may be new targets for treating and preventing corneal injuries in people with dry eye.
Diagram of myopic eye stretched front-to-back showing light focused in front of the retina

SUNY Optometry receives grant to reveal cellular and molecular mechanisms affecting myopia development

Myopia is a leading cause of vision impairment worldwide and is growing in prevalence, this study aims to provide a deeper understanding of the biology of myopia that will lead to new and more effective treatments.

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