Name: rs34671512
Published: September 21, 2022
License: Open Access

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs34671512

Current Build 156

Released September 21, 2022

Organism: Homo sapiens
Position: chr12:21239042 (GRCh38.p14) Help
The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.
Alleles: A>C
Variation Type: SNV Single Nucleotide Variation
Frequency: C=0.053878 (14261/264690, TOPMED)
C=0.045300 (11209/247440, GnomAD_exome)
C=0.052679 (11912/226124, ALFA) (+ 22 more)
C=0.054139 (7586/140122, GnomAD)
C=0.046322 (5431/117244, ExAC)
C=0.04564 (3592/78702, PAGE_STUDY)
C=0.05845 (755/12918, GO-ESP)
C=0.0447 (286/6404, 1000G_30x)
C=0.0443 (222/5008, 1000G)
C=0.0413 (185/4476, Estonian)
C=0.0547 (211/3854, ALSPAC)
C=0.0566 (210/3708, TWINSUK)
C=0.0210 (69/3284, PRJNA289433)
C=0.0455 (50/1100, Daghestan)
C=0.045 (45/998, GoNL)
C=0.003 (2/792, PRJEB37584)
C=0.008 (5/616, Vietnamese)
C=0.022 (13/600, NorthernSweden)
C=0.036 (19/534, MGP)
C=0.023 (8/354, PharmGKB)
C=0.056 (12/216, Qatari)
C=0.05 (2/40, GENOME_DK)
A=0.47 (14/30, SGDP_PRJ)
A=0.5 (2/4, Siberian)
C=0.5 (2/4, Siberian)

Clinical Significance: Reported in ClinVar
Gene : Consequence: SLCO1B1 : Missense Variant
LOC124902895 : Intron Variant
Publications: 3 citations
Genomic View: See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20231103111315

Population	Group	Sample Size	Ref Allele	Alt Allele	Ref HMOZ	Alt HMOZ	HTRZ	HWEP
Total	Global	226246	A=0.947318	C=0.052682	0.897545	0.002908	0.099547	0
European	Sub	192044	A=0.945742	C=0.054258	0.894389	0.002906	0.102706	0
African	Sub	7726	A=0.9333	C=0.0667	0.870567	0.003883	0.12555	0
African Others	Sub	262	A=0.958	C=0.042	0.916031	0.0	0.083969	0
African American	Sub	7464	A=0.9325	C=0.0675	0.868971	0.004019	0.12701	0
Asian	Sub	6404	A=0.9994	C=0.0006	0.998751	0.0	0.001249	0
East Asian	Sub	4554	A=0.9993	C=0.0007	0.998682	0.0	0.001318	0
Other Asian	Sub	1850	A=0.9995	C=0.0005	0.998919	0.0	0.001081	0
Latin American 1	Sub	818	A=0.935	C=0.065	0.875306	0.00489	0.119804	0
Latin American 2	Sub	1058	A=0.9603	C=0.0397	0.920605	0.0	0.079395	1
South Asian	Sub	292	A=0.959	C=0.041	0.917808	0.0	0.082192	0
Other	Sub	17904	A=0.95124	C=0.04876	0.906166	0.003686	0.090147	4

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

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Study	Population	Group	Sample Size	Ref Allele	Alt Allele
TopMed	Global	Study-wide	264690	A=0.946122	C=0.053878
gnomAD - Exomes	Global	Study-wide	247440	A=0.954700	C=0.045300
gnomAD - Exomes	European	Sub	133102	A=0.949753	C=0.050247
gnomAD - Exomes	Asian	Sub	48622	A=0.97154	C=0.02846
gnomAD - Exomes	American	Sub	34366	A=0.96447	C=0.03553
gnomAD - Exomes	African	Sub	15358	A=0.93391	C=0.06609
gnomAD - Exomes	Ashkenazi Jewish	Sub	9992	A=0.9366	C=0.0634
gnomAD - Exomes	Other	Sub	6000	A=0.9553	C=0.0447
Allele Frequency Aggregator	Total	Global	226124	A=0.947321	C=0.052679
Allele Frequency Aggregator	European	Sub	191940	A=0.945743	C=0.054257
Allele Frequency Aggregator	Other	Sub	17900	A=0.95123	C=0.04877
Allele Frequency Aggregator	African	Sub	7712	A=0.9334	C=0.0666
Allele Frequency Aggregator	Asian	Sub	6404	A=0.9994	C=0.0006
Allele Frequency Aggregator	Latin American 2	Sub	1058	A=0.9603	C=0.0397
Allele Frequency Aggregator	Latin American 1	Sub	818	A=0.935	C=0.065
Allele Frequency Aggregator	South Asian	Sub	292	A=0.959	C=0.041
gnomAD - Genomes	Global	Study-wide	140122	A=0.945861	C=0.054139
gnomAD - Genomes	European	Sub	75874	A=0.94851	C=0.05149
gnomAD - Genomes	African	Sub	42002	A=0.93617	C=0.06383
gnomAD - Genomes	American	Sub	13638	A=0.94963	C=0.05037
gnomAD - Genomes	Ashkenazi Jewish	Sub	3324	A=0.9413	C=0.0587
gnomAD - Genomes	East Asian	Sub	3130	A=0.9987	C=0.0013
gnomAD - Genomes	Other	Sub	2154	A=0.9480	C=0.0520
ExAC	Global	Study-wide	117244	A=0.953678	C=0.046322
ExAC	Europe	Sub	70758	A=0.94921	C=0.05079
ExAC	Asian	Sub	24748	A=0.97018	C=0.02982
ExAC	American	Sub	11372	A=0.96650	C=0.03350
ExAC	African	Sub	9476	A=0.9288	C=0.0712
ExAC	Other	Sub	890	A=0.952	C=0.048
The PAGE Study	Global	Study-wide	78702	A=0.95436	C=0.04564
The PAGE Study	AfricanAmerican	Sub	32516	A=0.93803	C=0.06197
The PAGE Study	Mexican	Sub	10810	A=0.96698	C=0.03302
The PAGE Study	Asian	Sub	8318	A=0.9990	C=0.0010
The PAGE Study	PuertoRican	Sub	7918	A=0.9524	C=0.0476
The PAGE Study	NativeHawaiian	Sub	4534	A=0.9852	C=0.0148
The PAGE Study	Cuban	Sub	4230	A=0.9357	C=0.0643
The PAGE Study	Dominican	Sub	3828	A=0.9417	C=0.0583
The PAGE Study	CentralAmerican	Sub	2450	A=0.9555	C=0.0445
The PAGE Study	SouthAmerican	Sub	1982	A=0.9662	C=0.0338
The PAGE Study	NativeAmerican	Sub	1260	A=0.9619	C=0.0381
The PAGE Study	SouthAsian	Sub	856	A=0.943	C=0.057
GO Exome Sequencing Project	Global	Study-wide	12918	A=0.94155	C=0.05845
GO Exome Sequencing Project	European American	Sub	8558	A=0.9441	C=0.0559
GO Exome Sequencing Project	African American	Sub	4360	A=0.9365	C=0.0635
1000Genomes_30x	Global	Study-wide	6404	A=0.9553	C=0.0447
1000Genomes_30x	African	Sub	1786	A=0.9328	C=0.0672
1000Genomes_30x	Europe	Sub	1266	A=0.9455	C=0.0545
1000Genomes_30x	South Asian	Sub	1202	A=0.9584	C=0.0416
1000Genomes_30x	East Asian	Sub	1170	A=0.9957	C=0.0043
1000Genomes_30x	American	Sub	980	A=0.957	C=0.043
1000Genomes	Global	Study-wide	5008	A=0.9557	C=0.0443
1000Genomes	African	Sub	1322	A=0.9349	C=0.0651
1000Genomes	East Asian	Sub	1008	A=0.9950	C=0.0050
1000Genomes	Europe	Sub	1006	A=0.9483	C=0.0517
1000Genomes	South Asian	Sub	978	A=0.951	C=0.049
1000Genomes	American	Sub	694	A=0.955	C=0.045
Genetic variation in the Estonian population	Estonian	Study-wide	4476	A=0.9587	C=0.0413
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.9453	C=0.0547
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.9434	C=0.0566
MxGDAR/Encodat-PGx	Global	Study-wide	3284	A=0.9790	C=0.0210
MxGDAR/Encodat-PGx	MxGDAR	Sub	3284	A=0.9790	C=0.0210
Genome-wide autozygosity in Daghestan	Global	Study-wide	1100	A=0.9545	C=0.0455
Genome-wide autozygosity in Daghestan	Daghestan	Sub	610	A=0.948	C=0.052
Genome-wide autozygosity in Daghestan	Near_East	Sub	138	A=0.986	C=0.014
Genome-wide autozygosity in Daghestan	Central Asia	Sub	116	A=0.983	C=0.017
Genome-wide autozygosity in Daghestan	Europe	Sub	102	A=0.922	C=0.078
Genome-wide autozygosity in Daghestan	South Asian	Sub	98	A=0.94	C=0.06
Genome-wide autozygosity in Daghestan	Caucasus	Sub	36	A=1.00	C=0.00
Genome of the Netherlands Release 5	Genome of the Netherlands	Study-wide	998	A=0.955	C=0.045
CNV burdens in cranial meningiomas	Global	Study-wide	792	A=0.997	C=0.003
CNV burdens in cranial meningiomas	CRM	Sub	792	A=0.997	C=0.003
A Vietnamese Genetic Variation Database	Global	Study-wide	616	A=0.992	C=0.008
Northern Sweden	ACPOP	Study-wide	600	A=0.978	C=0.022
Medical Genome Project healthy controls from Spanish population	Spanish controls	Study-wide	534	A=0.964	C=0.036
PharmGKB Aggregated	Global	Study-wide	354	A=0.977	C=0.023
PharmGKB Aggregated	PA148413897	Sub	354	A=0.977	C=0.023
Qatari	Global	Study-wide	216	A=0.944	C=0.056
The Danish reference pan genome	Danish	Study-wide	40	A=0.95	C=0.05
SGDP_PRJ	Global	Study-wide	30	A=0.47	C=0.53
Siberian	Global	Study-wide	4	A=0.5	C=0.5

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements

Sequence name	Change
GRCh38.p14 chr 12	NC_000012.12:g.21239042A>C
GRCh37.p13 chr 12	NC_000012.11:g.21391976A>C
SLCO1B1 RefSeqGene (LRG_1022)	NG_011745.1:g.112849A>C

Gene: SLCO1B1, solute carrier organic anion transporter family member 1B1 (plus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
SLCO1B1 transcript	NM_006446.5:c.1929A>C	L [TTA] > F [TTC]	Coding Sequence Variant
solute carrier organic anion transporter family member 1B1	NP_006437.3:p.Leu643Phe	L (Leu) > F (Phe)	Missense Variant

Gene: LOC124902895, uncharacterized LOC124902895 (minus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
LOC124902895 transcript	XR_007063239.1:n.	N/A	Intron Variant

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Allele: C (allele ID: 331512 )

ClinVar Accession	Disease Names	Clinical Significance
RCV000321358.9	Rotor syndrome	Benign
RCV001723891.1	not provided	Benign

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement	A=	C
GRCh38.p14 chr 12	NC_000012.12:g.21239042=	NC_000012.12:g.21239042A>C
GRCh37.p13 chr 12	NC_000012.11:g.21391976=	NC_000012.11:g.21391976A>C
SLCO1B1 RefSeqGene (LRG_1022)	NG_011745.1:g.112849=	NG_011745.1:g.112849A>C
SLCO1B1 transcript	NM_006446.5:c.1929=	NM_006446.5:c.1929A>C
SLCO1B1 transcript	NM_006446.4:c.1929=	NM_006446.4:c.1929A>C
solute carrier organic anion transporter family member 1B1	NP_006437.3:p.Leu643=	NP_006437.3:p.Leu643Phe

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

101 SubSNP, 24 Frequency, 2 ClinVar submissions

No	Submitter	Submission ID	Date (Build)
1	APPLERA_GI	ss48422820	Mar 14, 2006 (126)
2	PERLEGEN	ss69103293	May 18, 2007 (127)
3	PHARMGKB_AB_DME	ss84165356	Dec 16, 2007 (130)
4	CNG	ss98335542	Feb 06, 2009 (130)
5	SNP500CANCER	ss105440262	Feb 06, 2009 (130)
6	PMT	ss120239965	Dec 01, 2009 (131)
7	1000GENOMES	ss225645185	Jul 14, 2010 (132)
8	1000GENOMES	ss235854602	Jul 15, 2010 (132)
9	NHLBI-ESP	ss342351485	May 09, 2011 (134)
10	ILLUMINA	ss483039603	May 04, 2012 (137)
11	ILLUMINA	ss483746302	May 04, 2012 (137)
12	1000GENOMES	ss491038306	May 04, 2012 (137)
13	EXOME_CHIP	ss491465355	May 04, 2012 (137)
14	ILLUMINA	ss535946207	Sep 08, 2015 (146)
15	SSMP	ss658576100	Apr 25, 2013 (138)
16	ILLUMINA	ss779515580	Sep 08, 2015 (146)
17	ILLUMINA	ss780908773	Sep 08, 2015 (146)
18	ILLUMINA	ss782316711	Sep 08, 2015 (146)
19	ILLUMINA	ss783596245	Sep 08, 2015 (146)
20	ILLUMINA	ss834985998	Sep 08, 2015 (146)
21	EVA-GONL	ss989317577	Aug 21, 2014 (142)
22	JMKIDD_LAB	ss1078305824	Aug 21, 2014 (142)
23	1000GENOMES	ss1344207289	Aug 21, 2014 (142)
24	HAMMER_LAB	ss1397628281	Sep 08, 2015 (146)
25	EVA_GENOME_DK	ss1576156204	Apr 01, 2015 (144)
26	EVA_DECODE	ss1598990250	Apr 01, 2015 (144)
27	EVA_UK10K_ALSPAC	ss1628167931	Apr 01, 2015 (144)
28	EVA_UK10K_TWINSUK	ss1671161964	Apr 01, 2015 (144)
29	EVA_EXAC	ss1690820109	Apr 01, 2015 (144)
30	EVA_MGP	ss1711323342	Apr 01, 2015 (144)
31	ILLUMINA	ss1752060081	Sep 08, 2015 (146)
32	HAMMER_LAB	ss1807153243	Sep 08, 2015 (146)
33	ILLUMINA	ss1917871603	Feb 12, 2016 (147)
34	WEILL_CORNELL_DGM	ss1932682108	Feb 12, 2016 (147)
35	ILLUMINA	ss1946333571	Feb 12, 2016 (147)
36	ILLUMINA	ss1959419567	Feb 12, 2016 (147)
37	JJLAB	ss2027088417	Sep 14, 2016 (149)
38	ILLUMINA	ss2095032157	Dec 20, 2016 (150)
39	USC_VALOUEV	ss2155414189	Dec 20, 2016 (150)
40	HUMAN_LONGEVITY	ss2188378580	Dec 20, 2016 (150)
41	ILLUMINA	ss2632934735	Nov 08, 2017 (151)
42	ILLUMINA	ss2632934736	Nov 08, 2017 (151)
43	ILLUMINA	ss2632934737	Nov 08, 2017 (151)
44	ILLUMINA	ss2710756147	Nov 08, 2017 (151)
45	GNOMAD	ss2739676313	Nov 08, 2017 (151)
46	GNOMAD	ss2748826425	Nov 08, 2017 (151)
47	GNOMAD	ss2908179811	Nov 08, 2017 (151)
48	AFFY	ss2984969957	Nov 08, 2017 (151)
49	SWEGEN	ss3009331092	Nov 08, 2017 (151)
50	ILLUMINA	ss3021413103	Nov 08, 2017 (151)
51	CSIRBIOHTS	ss3029638282	Nov 08, 2017 (151)
52	CSHL	ss3349960957	Nov 08, 2017 (151)
53	ILLUMINA	ss3626833526	Oct 12, 2018 (152)
54	ILLUMINA	ss3626833527	Oct 12, 2018 (152)
55	ILLUMINA	ss3630945874	Oct 12, 2018 (152)
56	ILLUMINA	ss3634495022	Oct 12, 2018 (152)
57	ILLUMINA	ss3640202355	Oct 12, 2018 (152)
58	ILLUMINA	ss3644586529	Oct 12, 2018 (152)
59	BIOINF_KMB_FNS_UNIBA	ss3645240570	Oct 12, 2018 (152)
60	OMUKHERJEE_ADBS	ss3646439213	Oct 12, 2018 (152)
61	ILLUMINA	ss3651787278	Oct 12, 2018 (152)
62	ILLUMINA	ss3651787279	Oct 12, 2018 (152)
63	ILLUMINA	ss3653742508	Oct 12, 2018 (152)
64	EGCUT_WGS	ss3676646847	Jul 13, 2019 (153)
65	EVA_DECODE	ss3693260712	Jul 13, 2019 (153)
66	ILLUMINA	ss3725309358	Jul 13, 2019 (153)
67	ACPOP	ss3738837562	Jul 13, 2019 (153)
68	ILLUMINA	ss3744392926	Jul 13, 2019 (153)
69	ILLUMINA	ss3744795735	Jul 13, 2019 (153)
70	PAGE_CC	ss3771679215	Jul 13, 2019 (153)
71	ILLUMINA	ss3772295258	Jul 13, 2019 (153)
72	KHV_HUMAN_GENOMES	ss3815548952	Jul 13, 2019 (153)
73	EVA	ss3824711317	Apr 26, 2020 (154)
74	EVA	ss3825817709	Apr 26, 2020 (154)
75	EVA	ss3833014876	Apr 26, 2020 (154)
76	SGDP_PRJ	ss3877845724	Apr 26, 2020 (154)
77	FSA-LAB	ss3984023437	Apr 26, 2021 (155)
78	EVA	ss3984449741	Apr 26, 2021 (155)
79	EVA	ss3984663701	Apr 26, 2021 (155)
80	EVA	ss3986562238	Apr 26, 2021 (155)
81	TOPMED	ss4911221782	Apr 26, 2021 (155)
82	EVA	ss5237508242	Apr 26, 2021 (155)
83	EVA	ss5237659613	Oct 13, 2022 (156)
84	1000G_HIGH_COVERAGE	ss5290066286	Oct 13, 2022 (156)
85	TRAN_CS_UWATERLOO	ss5314434931	Oct 13, 2022 (156)
86	EVA	ss5404383965	Oct 13, 2022 (156)
87	HUGCELL_USP	ss5484925976	Oct 13, 2022 (156)
88	EVA	ss5510620097	Oct 13, 2022 (156)
89	EVA	ss5512473932	Oct 13, 2022 (156)
90	1000G_HIGH_COVERAGE	ss5587123463	Oct 13, 2022 (156)
91	SANFORD_IMAGENETICS	ss5624296750	Oct 13, 2022 (156)
92	SANFORD_IMAGENETICS	ss5652740838	Oct 13, 2022 (156)
93	EVA	ss5800175383	Oct 13, 2022 (156)
94	EVA	ss5837691298	Oct 13, 2022 (156)
95	EVA	ss5847405688	Oct 13, 2022 (156)
96	EVA	ss5847662895	Oct 13, 2022 (156)
97	EVA	ss5848347717	Oct 13, 2022 (156)
98	EVA	ss5850291963	Oct 13, 2022 (156)
99	EVA	ss5903575512	Oct 13, 2022 (156)
100	EVA	ss5944091284	Oct 13, 2022 (156)
101	EVA	ss5979385059	Oct 13, 2022 (156)
102	1000Genomes	NC_000012.11 - 21391976	Oct 12, 2018 (152)
103	1000Genomes_30x	NC_000012.12 - 21239042	Oct 13, 2022 (156)
104	The Avon Longitudinal Study of Parents and Children	NC_000012.11 - 21391976	Oct 12, 2018 (152)
105	Genome-wide autozygosity in Daghestan	NC_000012.10 - 21283243	Apr 26, 2020 (154)
106	Genetic variation in the Estonian population	NC_000012.11 - 21391976	Oct 12, 2018 (152)
107	ExAC	NC_000012.11 - 21391976	Oct 12, 2018 (152)
108	The Danish reference pan genome	NC_000012.11 - 21391976	Apr 26, 2020 (154)
109	gnomAD - Genomes	NC_000012.12 - 21239042	Apr 26, 2021 (155)
110	gnomAD - Exomes	NC_000012.11 - 21391976	Jul 13, 2019 (153)
111	GO Exome Sequencing Project	NC_000012.11 - 21391976	Oct 12, 2018 (152)
112	Genome of the Netherlands Release 5	NC_000012.11 - 21391976	Apr 26, 2020 (154)
113	Medical Genome Project healthy controls from Spanish population	NC_000012.11 - 21391976	Apr 26, 2020 (154)
114	Northern Sweden	NC_000012.11 - 21391976	Jul 13, 2019 (153)
115	The PAGE Study	NC_000012.12 - 21239042	Jul 13, 2019 (153)
116	CNV burdens in cranial meningiomas	NC_000012.11 - 21391976	Apr 26, 2021 (155)
117	MxGDAR/Encodat-PGx	NC_000012.11 - 21391976	Apr 26, 2021 (155)
118	PharmGKB Aggregated	NC_000012.12 - 21239042	Apr 26, 2020 (154)
119	Qatari	NC_000012.11 - 21391976	Apr 26, 2020 (154)
120	SGDP_PRJ	NC_000012.11 - 21391976	Apr 26, 2020 (154)
121	Siberian	NC_000012.11 - 21391976	Apr 26, 2020 (154)
122	TopMed	NC_000012.12 - 21239042	Apr 26, 2021 (155)
123	UK 10K study - Twins	NC_000012.11 - 21391976	Oct 12, 2018 (152)
124	A Vietnamese Genetic Variation Database	NC_000012.11 - 21391976	Jul 13, 2019 (153)
125	ALFA	NC_000012.12 - 21239042	Apr 26, 2021 (155)
126	ClinVar	RCV000321358.9	Oct 13, 2022 (156)
127	ClinVar	RCV001723891.1	Oct 13, 2022 (156)

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID	History Updated (Build)
rs61617271	May 27, 2008 (130)

Added to this RefSNP Cluster:

Submission IDs	Observation SPDI	Canonical SPDI	Source RSIDs
99256, ss483039603, ss1397628281, ss1598990250	NC_000012.10:21283242:A:C	NC_000012.12:21239041:A:C	(self)
56925983, 31608641, 22385095, 1110116, 2875891, 8904295, 1168802, 14103899, 439102, 12122427, 213193, 2742, 14724038, 29862704, 7930543, 31608641, 7013600, ss225645185, ss235854602, ss342351485, ss483746302, ss491038306, ss491465355, ss535946207, ss658576100, ss779515580, ss780908773, ss782316711, ss783596245, ss834985998, ss989317577, ss1078305824, ss1344207289, ss1576156204, ss1628167931, ss1671161964, ss1690820109, ss1711323342, ss1752060081, ss1807153243, ss1917871603, ss1932682108, ss1946333571, ss1959419567, ss2027088417, ss2095032157, ss2155414189, ss2632934735, ss2632934736, ss2632934737, ss2710756147, ss2739676313, ss2748826425, ss2908179811, ss2984969957, ss3009331092, ss3021413103, ss3029638282, ss3349960957, ss3626833526, ss3626833527, ss3630945874, ss3634495022, ss3640202355, ss3644586529, ss3646439213, ss3651787278, ss3651787279, ss3653742508, ss3676646847, ss3738837562, ss3744392926, ss3744795735, ss3772295258, ss3824711317, ss3825817709, ss3833014876, ss3877845724, ss3984023437, ss3984449741, ss3984663701, ss3986562238, ss5237508242, ss5404383965, ss5510620097, ss5512473932, ss5624296750, ss5652740838, ss5800175383, ss5837691298, ss5847405688, ss5847662895, ss5848347717, ss5944091284, ss5979385059	NC_000012.11:21391975:A:C	NC_000012.12:21239041:A:C	(self)
RCV000321358.9, RCV001723891.1, 74649398, 401392286, 900684, 2697, 126767439, 6541596660, ss2188378580, ss3645240570, ss3693260712, ss3725309358, ss3771679215, ss3815548952, ss4911221782, ss5237659613, ss5290066286, ss5314434931, ss5484925976, ss5587123463, ss5850291963, ss5903575512	NC_000012.12:21239041:A:C	NC_000012.12:21239041:A:C	(self)
ss48422820, ss69103293, ss84165356, ss98335542, ss105440262, ss120239965	NT_009714.17:14152099:A:C	NC_000012.12:21239041:A:C	(self)

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

3 citations for rs34671512

PMID	Title	Author	Year	Journal
22147369	Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition.	Ramsey LB et al.	2012	Genome research
29898760	A cost effective RFLP method to genotype Solute carrier organic anion 1B1 (SLCO1B1) c.1929A>C (p.Leu643Phe, rs34671512); a variant with potential effect on rosuvastatin pharmacokinetics.	Soko ND et al.	2018	BMC research notes
33875422	Pharmacogene Sequencing of a Gabonese Population with Severe Plasmodium falciparum Malaria Reveals Multiple Novel Variants with Putative Relevance for Antimalarial Treatment.	Pernaute-Lau L et al.	2021	Antimicrobial agents and chemotherapy

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

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Genomic regions, transcripts, and products
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NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
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dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

Reference SNP (rs) Report

rs34671512