Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

dbSNP Short Genetic Variations

Examples: rs268, BRCA1 and more Advanced search

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs2069526

Current Build 157

Released September 3, 2024

Organism
Homo sapiens
Position
chr15:74749000 (GRCh38.p14) Help

The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.

Alleles
T>G
Variation Type
SNV Single Nucleotide Variation
Frequency
G=0.053311 (14111/264690, TOPMED)
G=0.029481 (6568/222786, ALFA)
G=0.053976 (8048/149102, GnomAD_genomes) (+ 22 more)
G=0.06834 (5377/78682, PAGE_STUDY)
G=0.04814 (3728/77444, 38KJPN)
G=0.0514 (372/7234, Korea4K)
G=0.0717 (459/6404, 1000G_30X)
G=0.0711 (356/5008, 1000G)
G=0.0339 (152/4480, Estonian)
G=0.0195 (75/3854, ALSPAC)
G=0.0224 (83/3708, TWINSUK)
G=0.0447 (131/2930, KOREAN)
G=0.0708 (134/1892, HapMap)
G=0.0513 (94/1832, Korea1K)
G=0.019 (19/998, GoNL)
G=0.080 (63/788, PRJEB37584)
G=0.062 (37/600, NorthernSweden)
G=0.093 (33/356, PharmGKB)
G=0.083 (18/216, Qatari)
G=0.132 (28/212, Vietnamese)
T=0.50 (27/54, SGDP_PRJ)
G=0.50 (27/54, SGDP_PRJ)
G=0.03 (1/40, GENOME_DK)
T=0.5 (2/4, Siberian)
G=0.5 (2/4, Siberian)
Clinical Significance
Not Reported in ClinVar
Gene : Consequence
CYP1A2 : Intron Variant
Publications
10 citations
Genomic View
See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20231103111315
Population Group Sample Size Ref Allele Alt Allele Ref HMOZ Alt HMOZ HTRZ HWEP
Total Global 222786 T=0.970519 G=0.029481 0.942357 0.00132 0.056323 15
European Sub 191860 T=0.976983 G=0.023017 0.95454 0.000573 0.044887 0
African Sub 10128 T=0.89386 G=0.10614 0.799171 0.011453 0.189376 0
African Others Sub 348 T=0.882 G=0.118 0.775862 0.011494 0.212644 0
African American Sub 9780 T=0.8943 G=0.1057 0.8 0.011452 0.188548 0
Asian Sub 774 T=0.961 G=0.039 0.922481 0.0 0.077519 0
East Asian Sub 628 T=0.962 G=0.038 0.923567 0.0 0.076433 0
Other Asian Sub 146 T=0.959 G=0.041 0.917808 0.0 0.082192 0
Latin American 1 Sub 840 T=0.974 G=0.026 0.947619 0.0 0.052381 0
Latin American 2 Sub 6888 T=0.9582 G=0.0418 0.917247 0.000871 0.081882 1
South Asian Sub 5048 T=0.9087 G=0.0913 0.826862 0.009509 0.163629 0
Other Sub 7248 T=0.9619 G=0.0381 0.925773 0.001932 0.072296 0


Help

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

Download
Study Population Group Sample Size Ref Allele Alt Allele
TopMed Global Study-wide 264690 T=0.946689 G=0.053311
Allele Frequency Aggregator Total Global 222786 T=0.970519 G=0.029481
Allele Frequency Aggregator European Sub 191860 T=0.976983 G=0.023017
Allele Frequency Aggregator African Sub 10128 T=0.89386 G=0.10614
Allele Frequency Aggregator Other Sub 7248 T=0.9619 G=0.0381
Allele Frequency Aggregator Latin American 2 Sub 6888 T=0.9582 G=0.0418
Allele Frequency Aggregator South Asian Sub 5048 T=0.9087 G=0.0913
Allele Frequency Aggregator Latin American 1 Sub 840 T=0.974 G=0.026
Allele Frequency Aggregator Asian Sub 774 T=0.961 G=0.039
gnomAD v4 - Genomes Global Study-wide 149102 T=0.946024 G=0.053976
gnomAD v4 - Genomes European Sub 78590 T=0.97421 G=0.02579
gnomAD v4 - Genomes African Sub 41470 T=0.89301 G=0.10699
gnomAD v4 - Genomes American Sub 15282 T=0.96466 G=0.03534
gnomAD v4 - Genomes East Asian Sub 5184 T=0.9213 G=0.0787
gnomAD v4 - Genomes South Asian Sub 4812 T=0.9133 G=0.0867
gnomAD v4 - Genomes Ashkenazi Jewish Sub 3470 T=0.9424 G=0.0576
gnomAD v4 - Genomes Middle Eastern sub 294 T=0.935 G=0.065
The PAGE Study Global Study-wide 78682 T=0.93166 G=0.06834
The PAGE Study AfricanAmerican Sub 32516 T=0.89497 G=0.10503
The PAGE Study Mexican Sub 10810 T=0.95883 G=0.04117
The PAGE Study Asian Sub 8314 T=0.9503 G=0.0497
The PAGE Study PuertoRican Sub 7918 T=0.9638 G=0.0362
The PAGE Study NativeHawaiian Sub 4522 T=0.9761 G=0.0239
The PAGE Study Cuban Sub 4230 T=0.9681 G=0.0319
The PAGE Study Dominican Sub 3828 T=0.9373 G=0.0627
The PAGE Study CentralAmerican Sub 2450 T=0.9551 G=0.0449
The PAGE Study SouthAmerican Sub 1980 T=0.9626 G=0.0374
The PAGE Study NativeAmerican Sub 1260 T=0.9571 G=0.0429
The PAGE Study SouthAsian Sub 854 T=0.888 G=0.112
38KJPN JAPANESE Study-wide 77444 T=0.95186 G=0.04814
Korean Genome Project 4K KOREAN Study-wide 7234 T=0.9486 G=0.0514
1000Genomes_30X Global Study-wide 6404 T=0.9283 G=0.0717
1000Genomes_30X African Sub 1786 T=0.8723 G=0.1277
1000Genomes_30X Europe Sub 1266 T=0.9803 G=0.0197
1000Genomes_30X South Asian Sub 1202 T=0.9318 G=0.0682
1000Genomes_30X East Asian Sub 1170 T=0.9137 G=0.0863
1000Genomes_30X American Sub 980 T=0.977 G=0.023
1000Genomes Global Study-wide 5008 T=0.9289 G=0.0711
1000Genomes African Sub 1322 T=0.8767 G=0.1233
1000Genomes East Asian Sub 1008 T=0.9157 G=0.0843
1000Genomes Europe Sub 1006 T=0.9761 G=0.0239
1000Genomes South Asian Sub 978 T=0.931 G=0.069
1000Genomes American Sub 694 T=0.976 G=0.024
Genetic variation in the Estonian population Estonian Study-wide 4480 T=0.9661 G=0.0339
The Avon Longitudinal Study of Parents and Children PARENT AND CHILD COHORT Study-wide 3854 T=0.9805 G=0.0195
UK 10K study - Twins TWIN COHORT Study-wide 3708 T=0.9776 G=0.0224
KOREAN population from KRGDB KOREAN Study-wide 2930 T=0.9553 G=0.0447
HapMap Global Study-wide 1892 T=0.9292 G=0.0708
HapMap American Sub 770 T=0.939 G=0.061
HapMap African Sub 692 T=0.909 G=0.091
HapMap Asian Sub 254 T=0.933 G=0.067
HapMap Europe Sub 176 T=0.960 G=0.040
Korean Genome Project KOREAN Study-wide 1832 T=0.9487 G=0.0513
Genome of the Netherlands Release 5 Genome of the Netherlands Study-wide 998 T=0.981 G=0.019
CNV burdens in cranial meningiomas Global Study-wide 788 T=0.920 G=0.080
CNV burdens in cranial meningiomas CRM Sub 788 T=0.920 G=0.080
Northern Sweden ACPOP Study-wide 600 T=0.938 G=0.062
PharmGKB Aggregated Global Study-wide 356 T=0.907 G=0.093
PharmGKB Aggregated PA149530875 Sub 356 T=0.907 G=0.093
Qatari Global Study-wide 216 T=0.917 G=0.083
A Vietnamese Genetic Variation Database Global Study-wide 212 T=0.868 G=0.132
SGDP_PRJ Global Study-wide 54 T=0.50 G=0.50
The Danish reference pan genome Danish Study-wide 40 T=0.97 G=0.03
Siberian Global Study-wide 4 T=0.5 G=0.5
Help

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements
Sequence name Change
GRCh38.p14 chr 15 NC_000015.10:g.74749000T>G
GRCh37.p13 chr 15 NC_000015.9:g.75041341T>G
CYP1A1-CYP1A2 RefSeqGene NG_008431.2:g.31459T>G
CYP1A2 RefSeqGene (LRG_1274) NG_061543.1:g.5156T>G
LOC110467516 genomic region NG_055245.1:g.4670T>G
Gene: CYP1A2, cytochrome P450 family 1 subfamily A member 2 (plus strand)
Molecule type Change Amino acid[Codon] SO Term
CYP1A2 transcript NM_000761.5:c.-10+103T>G N/A Intron Variant
Help

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar
Help

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement T= G
GRCh38.p14 chr 15 NC_000015.10:g.74749000= NC_000015.10:g.74749000T>G
GRCh37.p13 chr 15 NC_000015.9:g.75041341= NC_000015.9:g.75041341T>G
CYP1A1-CYP1A2 RefSeqGene NG_008431.2:g.31459= NG_008431.2:g.31459T>G
CYP1A2 RefSeqGene (LRG_1274) NG_061543.1:g.5156= NG_061543.1:g.5156T>G
LOC110467516 genomic region NG_055245.1:g.4670= NG_055245.1:g.4670T>G
CYP1A2 transcript NM_000761.3:c.-10+103= NM_000761.3:c.-10+103T>G
CYP1A2 transcript NM_000761.5:c.-10+103= NM_000761.5:c.-10+103T>G
Help

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

118 SubSNP, 23 Frequency submissions
No Submitter Submission ID Date (Build)
1 UUGC ss2981600 Jun 15, 2001 (96)
2 TSC-CSHL ss3382510 Sep 28, 2001 (100)
3 RIKENSNPRC ss6311574 Feb 20, 2003 (111)
4 PERLEGEN ss23995690 Sep 20, 2004 (123)
5 NEBERTDW ss28515499 Sep 24, 2004 (126)
6 BIOVENTURES ss32475098 May 24, 2005 (125)
7 SNP500CANCER ss48293695 Mar 10, 2006 (126)
8 AFFY ss66123323 Nov 30, 2006 (127)
9 ILLUMINA ss75263874 Dec 07, 2007 (129)
10 CGM_KYOTO ss76860105 Dec 07, 2007 (129)
11 KRIBB_YJKIM ss81679260 Dec 14, 2007 (130)
12 PHARMGKB_AB_DME ss84158694 Dec 16, 2007 (130)
13 SHGC ss99307532 Feb 06, 2009 (130)
14 ILLUMINA-UK ss118287258 Feb 14, 2009 (130)
15 ILLUMINA ss153842597 Dec 01, 2009 (131)
16 ILLUMINA ss159355654 Dec 01, 2009 (131)
17 ILLUMINA ss160497382 Dec 01, 2009 (131)
18 ILLUMINA ss173093959 Jul 04, 2010 (132)
19 BUSHMAN ss201038379 Jul 04, 2010 (132)
20 1000GENOMES ss226976362 Jul 14, 2010 (132)
21 1000GENOMES ss243214194 Jul 15, 2010 (132)
22 GMI ss282318918 May 04, 2012 (137)
23 ILLUMINA ss410811992 Sep 17, 2011 (135)
24 ILLUMINA ss480408860 May 04, 2012 (137)
25 ILLUMINA ss480422129 May 04, 2012 (137)
26 ILLUMINA ss481204189 Sep 08, 2015 (146)
27 ILLUMINA ss485001975 May 04, 2012 (137)
28 ILLUMINA ss537033540 Sep 08, 2015 (146)
29 TISHKOFF ss564579140 Apr 25, 2013 (138)
30 SSMP ss660315787 Apr 25, 2013 (138)
31 ILLUMINA ss778698689 Sep 08, 2015 (146)
32 ILLUMINA ss782947288 Sep 08, 2015 (146)
33 ILLUMINA ss783909735 Sep 08, 2015 (146)
34 ILLUMINA ss832203135 Sep 08, 2015 (146)
35 ILLUMINA ss832867563 Jul 13, 2019 (153)
36 ILLUMINA ss834157579 Sep 08, 2015 (146)
37 EVA-GONL ss991955437 Aug 21, 2014 (142)
38 1000GENOMES ss1354127363 Aug 21, 2014 (142)
39 DDI ss1427677610 Apr 01, 2015 (144)
40 EVA_GENOME_DK ss1577703182 Apr 01, 2015 (144)
41 EVA_UK10K_ALSPAC ss1633356811 Apr 01, 2015 (144)
42 EVA_UK10K_TWINSUK ss1676350844 Apr 01, 2015 (144)
43 EVA_DECODE ss1695981776 Apr 01, 2015 (144)
44 EVA_SVP ss1713502763 Apr 01, 2015 (144)
45 ILLUMINA ss1752171273 Sep 08, 2015 (146)
46 HAMMER_LAB ss1808277880 Sep 08, 2015 (146)
47 WEILL_CORNELL_DGM ss1935358587 Feb 12, 2016 (147)
48 ILLUMINA ss1959626383 Feb 12, 2016 (147)
49 JJLAB ss2028461523 Sep 14, 2016 (149)
50 USC_VALOUEV ss2156868806 Dec 20, 2016 (150)
51 HUMAN_LONGEVITY ss2208164813 Dec 20, 2016 (150)
52 SYSTEMSBIOZJU ss2628725574 Nov 08, 2017 (151)
53 ILLUMINA ss2633251308 Nov 08, 2017 (151)
54 GRF ss2701347560 Nov 08, 2017 (151)
55 ILLUMINA ss2710820365 Nov 08, 2017 (151)
56 GNOMAD ss2936801925 Nov 08, 2017 (151)
57 AFFY ss2985046783 Nov 08, 2017 (151)
58 AFFY ss2985680241 Nov 08, 2017 (151)
59 SWEGEN ss3013550577 Nov 08, 2017 (151)
60 ILLUMINA ss3021649403 Nov 08, 2017 (151)
61 ILLUMINA ss3627401420 Oct 12, 2018 (152)
62 ILLUMINA ss3631242636 Oct 12, 2018 (152)
63 ILLUMINA ss3633807912 Oct 12, 2018 (152)
64 ILLUMINA ss3634614895 Oct 12, 2018 (152)
65 ILLUMINA ss3635496702 Oct 12, 2018 (152)
66 ILLUMINA ss3636304921 Oct 12, 2018 (152)
67 ILLUMINA ss3637248009 Oct 12, 2018 (152)
68 ILLUMINA ss3638095670 Oct 12, 2018 (152)
69 ILLUMINA ss3640322216 Oct 12, 2018 (152)
70 ILLUMINA ss3643079188 Oct 12, 2018 (152)
71 OMUKHERJEE_ADBS ss3646477150 Oct 12, 2018 (152)
72 ILLUMINA ss3652051091 Oct 12, 2018 (152)
73 ILLUMINA ss3653818977 Oct 12, 2018 (152)
74 EGCUT_WGS ss3680697606 Jul 13, 2019 (153)
75 ILLUMINA ss3725514471 Jul 13, 2019 (153)
76 ACPOP ss3741066415 Jul 13, 2019 (153)
77 ILLUMINA ss3744915419 Jul 13, 2019 (153)
78 EVA ss3753294162 Jul 13, 2019 (153)
79 PAGE_CC ss3771841895 Jul 13, 2019 (153)
80 ILLUMINA ss3772413983 Jul 13, 2019 (153)
81 KHV_HUMAN_GENOMES ss3818599966 Jul 13, 2019 (153)
82 SGDP_PRJ ss3883259779 Apr 27, 2020 (154)
83 KRGDB ss3932477500 Apr 27, 2020 (154)
84 KOGIC ss3976480984 Apr 27, 2020 (154)
85 EVA ss3984704000 Apr 27, 2021 (155)
86 EVA ss4017710714 Apr 27, 2021 (155)
87 TOPMED ss4997226077 Apr 27, 2021 (155)
88 TOMMO_GENOMICS ss6157346980 Nov 01, 2024 (157)
89 EVA ss6205742215 Nov 01, 2024 (157)
90 EVA ss6269305175 Nov 01, 2024 (157)
91 EVA ss6315157295 Nov 01, 2024 (157)
92 EVA ss6322017913 Nov 01, 2024 (157)
93 EVA ss6322526134 Nov 01, 2024 (157)
94 EVA ss6333023117 Nov 01, 2024 (157)
95 EVA ss6349896113 Nov 01, 2024 (157)
96 KOGIC ss6392444773 Nov 01, 2024 (157)
97 GNOMAD ss6981064173 Nov 01, 2024 (157)
98 TOMMO_GENOMICS ss8216965585 Nov 01, 2024 (157)
99 EVA ss8237553874 Nov 01, 2024 (157)
100 1000G_HIGH_COVERAGE ss8299021703 Nov 01, 2024 (157)
101 EVA ss8315797264 Nov 01, 2024 (157)
102 EVA ss8420300618 Nov 01, 2024 (157)
103 HUGCELL_USP ss8492692934 Nov 01, 2024 (157)
104 1000G_HIGH_COVERAGE ss8600713801 Nov 01, 2024 (157)
105 SANFORD_IMAGENETICS ss8624365244 Nov 01, 2024 (157)
106 SANFORD_IMAGENETICS ss8657836135 Nov 01, 2024 (157)
107 TOMMO_GENOMICS ss8771002552 Nov 01, 2024 (157)
108 EVA ss8799942627 Nov 01, 2024 (157)
109 YY_MCH ss8815479396 Nov 01, 2024 (157)
110 EVA ss8828426677 Nov 01, 2024 (157)
111 EVA ss8847451974 Nov 01, 2024 (157)
112 EVA ss8847749758 Nov 01, 2024 (157)
113 EVA ss8876549150 Nov 01, 2024 (157)
114 EVA ss8949253583 Nov 01, 2024 (157)
115 EVA ss8979466987 Nov 01, 2024 (157)
116 EVA ss8981789403 Nov 01, 2024 (157)
117 EVA ss8981789404 Nov 01, 2024 (157)
118 EVA ss8982251119 Nov 01, 2024 (157)
119 1000Genomes NC_000015.9 - 75041341 Oct 12, 2018 (152)
120 1000Genomes_30X NC_000015.10 - 74749000 Nov 01, 2024 (157)
121 The Avon Longitudinal Study of Parents and Children NC_000015.9 - 75041341 Oct 12, 2018 (152)
122 Genetic variation in the Estonian population NC_000015.9 - 75041341 Oct 12, 2018 (152)
123 The Danish reference pan genome NC_000015.9 - 75041341 Apr 27, 2020 (154)
124 gnomAD v4 - Genomes NC_000015.10 - 74749000 Nov 01, 2024 (157)
125 Genome of the Netherlands Release 5 NC_000015.9 - 75041341 Apr 27, 2020 (154)
126 HapMap NC_000015.10 - 74749000 Apr 27, 2020 (154)
127 KOREAN population from KRGDB NC_000015.9 - 75041341 Apr 27, 2020 (154)
128 Korean Genome Project NC_000015.10 - 74749000 Apr 27, 2020 (154)
129 Korean Genome Project 4K NC_000015.10 - 74749000 Nov 01, 2024 (157)
130 Northern Sweden NC_000015.9 - 75041341 Jul 13, 2019 (153)
131 The PAGE Study NC_000015.10 - 74749000 Jul 13, 2019 (153)
132 CNV burdens in cranial meningiomas NC_000015.9 - 75041341 Apr 27, 2021 (155)
133 PharmGKB Aggregated NC_000015.10 - 74749000 Apr 27, 2020 (154)
134 Qatari NC_000015.9 - 75041341 Apr 27, 2020 (154)
135 SGDP_PRJ NC_000015.9 - 75041341 Apr 27, 2020 (154)
136 Siberian NC_000015.9 - 75041341 Apr 27, 2020 (154)
137 38KJPN NC_000015.10 - 74749000 Nov 01, 2024 (157)
138 TopMed NC_000015.10 - 74749000 Apr 27, 2021 (155)
139 UK 10K study - Twins NC_000015.9 - 75041341 Oct 12, 2018 (152)
140 A Vietnamese Genetic Variation Database NC_000015.9 - 75041341 Jul 13, 2019 (153)
141 ALFA NC_000015.10 - 74749000 Nov 01, 2024 (157)
Help

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID History Updated (Build)
rs17861148 Mar 10, 2006 (126)
rs57601484 Feb 27, 2009 (130)
rs61709032 May 27, 2008 (130)
Added to this RefSNP Cluster:
Submission IDs Observation SPDI Canonical SPDI Source RSIDs
ss118287258, ss201038379, ss282318918, ss480408860, ss1695981776, ss1713502763, ss3643079188 NC_000015.8:72828393:T:G NC_000015.10:74748999:T:G (self)
67222935, 37331429, 26435854, 3924183, 16659129, 39654894, 14351280, 253525, 17400517, 35276759, 9385160, 37331429, 8301250, ss226976362, ss243214194, ss480422129, ss481204189, ss485001975, ss537033540, ss564579140, ss660315787, ss778698689, ss782947288, ss783909735, ss832203135, ss832867563, ss834157579, ss991955437, ss1354127363, ss1427677610, ss1577703182, ss1633356811, ss1676350844, ss1752171273, ss1808277880, ss1935358587, ss1959626383, ss2028461523, ss2156868806, ss2628725574, ss2633251308, ss2701347560, ss2710820365, ss2936801925, ss2985046783, ss2985680241, ss3013550577, ss3021649403, ss3627401420, ss3631242636, ss3633807912, ss3634614895, ss3635496702, ss3636304921, ss3637248009, ss3638095670, ss3640322216, ss3646477150, ss3652051091, ss3653818977, ss3680697606, ss3741066415, ss3744915419, ss3753294162, ss3772413983, ss3883259779, ss3932477500, ss3984704000, ss4017710714, ss6269305175, ss6315157295, ss6322526134, ss6333023117, ss6349896113, ss8216965585, ss8237553874, ss8315797264, ss8420300618, ss8624365244, ss8657836135, ss8799942627, ss8828426677, ss8847451974, ss8847749758, ss8949253583, ss8979466987, ss8981789403, ss8981789404, ss8982251119 NC_000015.9:75041340:T:G NC_000015.10:74748999:T:G (self)
88239736, 508488295, 1295503, 32858985, 42296671, 1063364, 3606, 174722800, 212771737, 2955472658, ss2208164813, ss3725514471, ss3771841895, ss3818599966, ss3976480984, ss4997226077, ss6157346980, ss6205742215, ss6322017913, ss6392444773, ss6981064173, ss8299021703, ss8492692934, ss8600713801, ss8771002552, ss8815479396, ss8876549150 NC_000015.10:74748999:T:G NC_000015.10:74748999:T:G (self)
ss2981600, ss3382510, ss6311574, ss23995690, ss28515499, ss32475098, ss48293695, ss66123323, ss75263874, ss76860105, ss81679260, ss84158694, ss99307532, ss153842597, ss159355654, ss160497382, ss173093959, ss410811992 NT_010194.17:45831897:T:G NC_000015.10:74748999:T:G (self)
Help

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

10 citations for rs2069526
PMID Title Author Year Journal
20957336 CYP1A2*1F and GSTM1 alleles are associated with susceptibility to porphyria cutanea tarda. Wickliffe JK et al. 2011 Molecular medicine (Cambridge, Mass.)
21382071 Altered xanthine oxidase and N-acetyltransferase activity in obese children. Chiney MS et al. 2011 British journal of clinical pharmacology
21519338 Genetic variation in CYP3A43 explains racial difference in olanzapine clearance. Bigos KL et al. 2011 Molecular psychiatry
23157985 CYP1A2 rs762551 polymorphism contributes to cancer susceptibility: a meta-analysis from 19 case-control studies. Wang H et al. 2012 BMC cancer
24884825 Increased genetic diversity of ADME genes in African Americans compared with their putative ancestral source populations and implications for pharmacogenomics. Li J et al. 2014 BMC genetics
24944790 Screening for 392 polymorphisms in 141 pharmacogenes. Kim JY et al. 2014 Biomedical reports
26865042 Lack of association between polymorphisms in the CYP1A2 gene and risk of cancer: evidence from meta-analyses. Vukovic V et al. 2016 BMC cancer
27529241 The Risk of Congenital Heart Anomalies Following Prenatal Exposure to Serotonin Reuptake Inhibitors-Is Pharmacogenetics the Key? Daud AN et al. 2016 International journal of molecular sciences
28232737 Candidate Gene Association Studies of Anthracycline-induced Cardiotoxicity: A Systematic Review and Meta-analysis. Leong SL et al. 2017 Scientific reports
30093869 Biological Predictors of Clozapine Response: A Systematic Review. Samanaite R et al. 2018 Frontiers in psychiatry
Help

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:
Select flank length:

Genomic regions, transcripts, and products
Top▲ Help

NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

Software version is: 2.0.1.post825+45319f0