Leflunomide
- PMID: 32491731
- Bookshelf ID: NBK557799
Leflunomide
Excerpt
Leflunomide is a medication used in the management and treatment of rheumatoid arthritis. It is in the non-biological DMARDs class of medications. This activity reviews the indications, action, and contraindications for leflunomide as a valuable agent in treating and managing rheumatoid arthritis. This activity will highlight the mechanism of action, adverse event profile, and other key factors of leflunomide use in a clinical setting, pertinent to members of the interprofessional team in the care of patients with rheumatoid arthritis and related conditions.
Copyright © 2025, StatPearls Publishing LLC.
Conflict of interest statement
Sections
Similar articles
-
Etanercept.2023 Jul 24. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. 2023 Jul 24. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 31424836 Free Books & Documents.
-
Neonatal Abstinence Syndrome.2024 Apr 1. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. 2024 Apr 1. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 31855342 Free Books & Documents.
-
Carbidopa.2023 Jul 4. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. 2023 Jul 4. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 32119439 Free Books & Documents.
-
Biologic interventions for fatigue in rheumatoid arthritis.Cochrane Database Syst Rev. 2016 Jun 6;2016(6):CD008334. doi: 10.1002/14651858.CD008334.pub2. Cochrane Database Syst Rev. 2016. PMID: 27271314 Free PMC article. Review.
-
Depressing time: Waiting, melancholia, and the psychoanalytic practice of care.In: Kirtsoglou E, Simpson B, editors. The Time of Anthropology: Studies of Contemporary Chronopolitics. Abingdon: Routledge; 2020. Chapter 5. In: Kirtsoglou E, Simpson B, editors. The Time of Anthropology: Studies of Contemporary Chronopolitics. Abingdon: Routledge; 2020. Chapter 5. PMID: 36137063 Free Books & Documents. Review.
References
-
- Kaplan MJ. Leflunomide Aventis Pharma. Curr Opin Investig Drugs. 2001 Feb;2(2):222-30. - PubMed
-
- Goldenberg MM. Leflunomide, a novel immunomodulator for the treatment of active rheumatoid arthritis. Clin Ther. 1999 Nov;21(11):1837-52; discussion 1821. - PubMed
-
- Alldred A, Emery P. Leflunomide: a novel DMARD for the treatment of rheumatoid arthritis. Expert Opin Pharmacother. 2001 Jan;2(1):125-37. - PubMed
-
- Leflunomide for rheumatoid arthritis. Drug Ther Bull. 2000 Jul;38(7):52-4. - PubMed
-
- Dai Q, Xu L, Yu X. Efficacy and safety of leflunomide in psoriatic arthritis treatment: A single-arm meta-analysis. Int J Rheum Dis. 2019 Aug;22(8):1498-1505. - PubMed
Publication types
LinkOut - more resources
Full Text Sources