Ipilimumab
- PMID: 32491727
- Bookshelf ID: NBK557795
Ipilimumab
Excerpt
Ipilimumab is a medication used in the management and treatment of metastatic melanoma. It is in the CTLA-4 monoclonal antibody class of drugs. This activity illustrates the indications, action, and contraindications for Ipilimumab as a valuable agent in managing metastatic melanoma and several other tumors. This activity will highlight the mechanism of action, adverse event profile, and other key factors (e.g., off-label uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, relevant interactions) pertinent for members of the healthcare team in the management of patients with metastatic melanoma and related conditions.
Copyright © 2025, StatPearls Publishing LLC.
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References
-
- Monteiro FSM, Soares A, Debiasi M, Schutz FA, Maluf FC, Bastos DA, Sasse A, Cauduro CGS, Mendes GO, Ziegelmann PK, Fay AP. First-line Treatment of Metastatic Renal Cell Carcinoma in the Immuno-oncology Era: Systematic Review and Network Meta-analysis. Clin Genitourin Cancer. 2020 Aug;18(4):244-251.e4. - PubMed
-
- Thomas J, Leal A, Overman MJ. Clinical Development of Immunotherapy for Deficient Mismatch Repair Colorectal Cancer. Clin Colorectal Cancer. 2020 Jun;19(2):73-81. - PubMed
-
- Kudo M. Immuno-Oncology in Hepatocellular Carcinoma: 2017 Update. Oncology. 2017;93 Suppl 1:147-159. - PubMed
-
- Leach DR, Krummel MF, Allison JP. Enhancement of antitumor immunity by CTLA-4 blockade. Science. 1996 Mar 22;271(5256):1734-6. - PubMed
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