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<div id="header"> <div id="ncbi-image"> <a href="/"> <img width="145" height="66" border="0" alt="National Center for Biotechnology Information (NCBI)" src="/geo/img/ncbi_logo.gif" /> </a> </div> <div id="gds-image"> <a href="/sites/GDSbrowser/"> <img alt="GEO DataSet Browser" src="/geo/img/GDSbrowser_logo.png" /> </a> </div> <div id="geo-image"> <a href="/geo/"> <img border="0" alt="Gene Expression Omnibus (GEO)" src="/geo/img/geo_main.gif" /> </a> </div> </div> <div id="main"> <form enctype="application/x-www-form-urlencoded" name="GDSBrowserQuery" method="post" onsubmit="return false;" action="/sites/GDSbrowser" id="GDSBrowserQuery"> <div id="query"> <table summary="Query bar components"> <tr> <td> <div id="search_bar"><label for="term">Search for </label><input name="GDSBrowser_L.GDSBrowser_C.GDSBrowserQuery.Term" sid="1" type="text" id="term" value="" size="45" /> <button name="GDSBrowser_L.GDSBrowser_C.GDSBrowserQuery.Search" sid="1" id="SearchButton" submit="yes">Search</button> 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class="organism">Organism(s)</th><th class="platform">Platform</th><th class="series">Series</th><th id="samplesHeader" class="samples"><a name="GDSBrowser_L.GDSBrowser_C.DatasetTable_C.DatasetTable.bSortDown" sid="1" id="bSortDown" realname="GDSBrowser_L.GDSBrowser_C.DatasetTable_C.DatasetTable.bSortDown" submit="yes" href="?" onclick="return false;"><span title="Click to sort in descending order"><img alt="⇒" src="/geo/img/buttons/tri_right.png" /> Samples </span></a><input name="GDSBrowser_L.GDSBrowser_C.DatasetTable_C.DatasetTable.Sort" sid="1" type="hidden" value="" /></th></tr></table><div id="results_body"><table id="GDSTableBody"><tr id="gds6063" onclick="javascript:Portal.$send('GDSRowClick', {'gds': 6063})"><td class="acc">GDS6063</td><td class="title"><div>Influenza A effect on plasmacytoid dendritic cells</div></td><td class="species organism">Homo sapiens</td><td class="title-tt platform"><span title="Illumina HumanHT-12 V4.0 expression beadchip"><a href="/geo/query/acc.cgi?acc=GPL10558" target="_blank"> GPL10558</a></span></td><td class="title-tt series"><span title="Impact of influenza A on human plasmacytoid dendritic cells (pDC) gene expression"><a href="/geo/query/acc.cgi?acc=GSE68849" target="_blank"> GSE68849</a></span></td><td class="int samples">10</td></tr><tr id="gds6010" onclick="javascript:Portal.$send('GDSRowClick', {'gds': 6010})" class="even"><td class="acc">GDS6010</td><td class="title"><div>Influenza virus H5N1 infection of U251 astrocyte cell line: time course</div></td><td class="species organism">Homo sapiens</td><td class="title-tt platform"><span title="Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version)"><a href="/geo/query/acc.cgi?acc=GPL6480" target="_blank"> GPL6480</a></span></td><td class="title-tt series"><span title="Insights into responses of human astrocytes to H5N1 infection by transcriptional analysis"><a href="/geo/query/acc.cgi?acc=GSE66597" target="_blank"> GSE66597</a></span></td><td class="int samples">18</td></tr><tr id="gds5879" onclick="javascript:Portal.$send('GDSRowClick', {'gds': 5879})"><td class="acc">GDS5879</td><td class="title"><div>Pulmonary CDC11c+ cells from young and middle-age animals</div></td><td class="species organism">Mus musculus</td><td class="title-tt platform"><span title="Illumina MouseRef-8 v2.0 expression beadchip"><a href="/geo/query/acc.cgi?acc=GPL6885" target="_blank"> GPL6885</a></span></td><td class="title-tt series"><span title="Gene expression pattern of pulmonary CD11c+ cells from middle-aged and young mice."><a href="/geo/query/acc.cgi?acc=GSE71868" target="_blank"> GSE71868</a></span></td><td class="int samples">8</td></tr><tr id="gds5826" onclick="javascript:Portal.$send('GDSRowClick', {'gds': 5826})" class="even"><td class="acc">GDS5826</td><td class="title"><div>Multiple myeloma cell lines with acquired resistance to chemotherapeutic agent carfilzomib</div></td><td class="species organism">Homo sapiens</td><td class="title-tt platform"><span title="[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array"><a href="/geo/query/acc.cgi?acc=GPL570" target="_blank"> GPL570</a></span></td><td class="title-tt series"><span title="Comparison of the gene expression profiles of carfilzomib-resistant derivatives versus parental human myeloma cell lines"><a href="/geo/query/acc.cgi?acc=GSE69078" target="_blank"> GSE69078</a></span></td><td class="int samples">12</td></tr><tr id="gds5825" onclick="javascript:Portal.$send('GDSRowClick', {'gds': 5825})"><td class="acc">GDS5825</td><td class="title"><div>Interleukin-1α deficiency effect on injured spinal cord</div></td><td class="species organism">Mus musculus</td><td class="title-tt platform"><span title="[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]"><a href="/geo/query/acc.cgi?acc=GPL6246" target="_blank"> GPL6246</a></span></td><td class="title-tt series"><span title="Gene expression data of C57BL/6, Il1a-knockout and Il1b-knockout mice at 24 hours after spinal cord injury"><a href="/geo/query/acc.cgi?acc=GSE70302" target="_blank"> GSE70302</a></span></td><td class="int samples">12</td></tr><tr id="gds5881" onclick="javascript:Portal.$send('GDSRowClick', {'gds': 5881})" class="even"><td class="acc">GDS5881</td><td class="title"><div>Nebulin deficiency effect on the soleus</div></td><td class="species organism">Mus musculus</td><td class="title-tt platform"><span title="[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]"><a href="/geo/query/acc.cgi?acc=GPL6246" target="_blank"> GPL6246</a></span></td><td class="title-tt series"><span title="The effect of Nebulin-Deficiency on Skeletal Muscle"><a href="/geo/query/acc.cgi?acc=GSE70213" target="_blank"> GSE70213</a></span></td><td class="int samples">12</td></tr><tr id="gds5880" onclick="javascript:Portal.$send('GDSRowClick', {'gds': 5880})"><td class="acc">GDS5880</td><td class="title"><div>Nebulin deficiency effect on the quadriceps</div></td><td class="species organism">Mus musculus</td><td class="title-tt platform"><span title="[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]"><a href="/geo/query/acc.cgi?acc=GPL6246" target="_blank"> GPL6246</a></span></td><td class="title-tt series"><span title="The effect of Nebulin-Deficiency on Skeletal Muscle"><a href="/geo/query/acc.cgi?acc=GSE70213" target="_blank"> GSE70213</a></span></td><td class="int samples">12</td></tr><tr id="gds5913" onclick="javascript:Portal.$send('GDSRowClick', {'gds': 5913})" class="even"><td class="acc">GDS5913</td><td class="title"><div>SRPIN803 small molecule inhibitor of SRPK1 effect on retinal pigment epithelial cell line</div></td><td class="species organism">Homo sapiens</td><td class="title-tt platform"><span title="[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array"><a href="/geo/query/acc.cgi?acc=GPL570" target="_blank"> GPL570</a></span></td><td class="title-tt series"><span title="Expression Data from DMSO or SRPIN803 treated ARPE-19 cells"><a href="/geo/query/acc.cgi?acc=GSE62947" target="_blank"> GSE62947</a></span></td><td class="int samples">6</td></tr><tr id="gds5665" onclick="javascript:Portal.$send('GDSRowClick', {'gds': 5665})"><td class="acc">GDS5665</td><td class="title"><div>Pathogen-associated molecular-pattern curdlan effect on interleukin-2 deficient GM-CSF myeloid dendritic cells</div></td><td class="species organism">Mus musculus</td><td class="title-tt platform"><span title="[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]"><a href="/geo/query/acc.cgi?acc=GPL6246" target="_blank"> GPL6246</a></span></td><td class="title-tt series"><span title="Dendritic cell-derived IL-2 promotes apoptosis of terminally mature cells via a novel autocrine signaling pathway"><a href="/geo/query/acc.cgi?acc=GSE58120" target="_blank"> GSE58120</a></span></td><td class="int samples">12</td></tr><tr id="gds5662" onclick="javascript:Portal.$send('GDSRowClick', {'gds': 5662})" class="even"><td class="acc">GDS5662</td><td class="title"><div>Histone demethylase KDM3A-deficiency effect on estrogen-stimulated breast cancer cells in vitro</div></td><td class="species organism">Homo sapiens</td><td class="title-tt platform"><span title="Illumina HumanHT-12 V4.0 expression beadchip"><a href="/geo/query/acc.cgi?acc=GPL10558" target="_blank"> GPL10558</a></span></td><td class="title-tt series"><span title="Identification of KDM3A regulated genes in the ER positive breast cancer cell line MCF-7"><a href="/geo/query/acc.cgi?acc=GSE68918" target="_blank"> GSE68918</a></span></td><td class="int samples">11</td></tr><tr id="gds5948" onclick="javascript:Portal.$send('GDSRowClick', {'gds': 5948})"><td class="acc">GDS5948</td><td class="title"><div>Zipper-interacting protein kinase deficiency effect on coronary artery smooth muscle cells in vitro</div></td><td class="species organism">Homo sapiens</td><td class="title-tt platform"><span title="[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]"><a href="/geo/query/acc.cgi?acc=GPL6244" target="_blank"> GPL6244</a></span></td><td class="title-tt series"><span title="Effects of knockdown of ROCK1 and ZIPK on gene expression in cultured human vascular smooth muscle cells"><a href="/geo/query/acc.cgi?acc=GSE56819" target="_blank"> GSE56819</a></span></td><td class="int samples">6</td></tr><tr id="gds5659" onclick="javascript:Portal.$send('GDSRowClick', {'gds': 5659})" class="even"><td class="acc">GDS5659</td><td class="title"><div>Rho-associated kinase deficiency effect on coronary artery smooth muscle cells in vitro</div></td><td class="species organism">Homo sapiens</td><td class="title-tt platform"><span title="[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]"><a href="/geo/query/acc.cgi?acc=GPL6244" target="_blank"> GPL6244</a></span></td><td class="title-tt series"><span title="Effects of knockdown of ROCK1 and ZIPK on gene expression in cultured human vascular smooth muscle cells"><a href="/geo/query/acc.cgi?acc=GSE56819" target="_blank"> GSE56819</a></span></td><td class="int samples">6</td></tr><tr id="gds5658" onclick="javascript:Portal.$send('GDSRowClick', {'gds': 5658})"><td class="acc">GDS5658</td><td class="title"><div>Retinoid X receptor activation effect on stimulated RAW264.7 cells</div></td><td class="species organism">Mus musculus</td><td class="title-tt platform"><span title="[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array"><a href="/geo/query/acc.cgi?acc=GPL1261" target="_blank"> GPL1261</a></span></td><td class="title-tt series"><span title="Gene expression during ligands activation of RXR in activated RAW264.7 cells"><a href="/geo/query/acc.cgi?acc=GSE62107" target="_blank"> GSE62107</a></span></td><td class="int samples">6</td></tr><tr id="gds5661" onclick="javascript:Portal.$send('GDSRowClick', {'gds': 5661})" class="even"><td class="acc">GDS5661</td><td class="title"><div>Interleukin 7 and FLT-3 ligand effect on EML1 HSPC line expressing acute lymphoblastic leukemia TEL-AML1 fusion protein: time course</div></td><td class="species organism">Mus musculus</td><td class="title-tt platform"><span title="[MoGene-1_1-st] Affymetrix Mouse Gene 1.1 ST Array [transcript (gene) version]"><a href="/geo/query/acc.cgi?acc=GPL11533" target="_blank"> GPL11533</a></span></td><td class="title-tt series"><span title="Genes regulated in EML1 cells expressing the TEL-AML1 oncogene after 5 and 7 days of treatment with IL7 and FLT3 ligand."><a href="/geo/query/acc.cgi?acc=GSE64919" target="_blank"> GSE64919</a></span></td><td class="int samples">12</td></tr><tr id="gds5657" onclick="javascript:Portal.$send('GDSRowClick', {'gds': 5657})"><td class="acc">GDS5657</td><td class="title"><div>Transcription factor Cabut deficiency and overexpression effects on heads: time course</div></td><td class="species organism">Drosophila melanogaster</td><td class="title-tt platform"><span title="[Drosophila_2] Affymetrix Drosophila Genome 2.0 Array"><a href="/geo/query/acc.cgi?acc=GPL1322" target="_blank"> GPL1322</a></span></td><td class="title-tt series"><span title="Microarray data obtained from control, cbtRNAi and cbtOE flies"><a href="/geo/query/acc.cgi?acc=GSE67865" target="_blank"> GSE67865</a></span></td><td class="int samples">6</td></tr><tr id="gds5655" onclick="javascript:Portal.$send('GDSRowClick', {'gds': 5655})" class="even"><td class="acc">GDS5655</td><td class="title"><div>Lymphotoxin-β receptor agonist antibody effect on lipopolysaccharide-stimulated embryonic fibroblasts</div></td><td class="species organism">Mus musculus</td><td class="title-tt platform"><span title="Illumina MouseRef-8 v2.0 expression beadchip"><a href="/geo/query/acc.cgi?acc=GPL6885" target="_blank"> GPL6885</a></span></td><td class="title-tt series"><span title="Developmental LTbR synergistically activates TLR4 mediated inflammatory RelA/NF-kB response"><a href="/geo/query/acc.cgi?acc=GSE62301" target="_blank"> GSE62301</a></span></td><td class="int samples">4</td></tr><tr id="gds5656" onclick="javascript:Portal.$send('GDSRowClick', {'gds': 5656})"><td class="acc">GDS5656</td><td class="title"><div>Forkhead box O 1,3,4 muscle-specific knockout effect on fasted gastrocnemius muscle</div></td><td class="species organism">Mus musculus</td><td class="title-tt platform"><span title="[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array"><a href="/geo/query/acc.cgi?acc=GPL1261" target="_blank"> GPL1261</a></span></td><td class="title-tt series"><span title="The FoxO signature in protein breakdown"><a href="/geo/query/acc.cgi?acc=GSE52667" target="_blank"> GSE52667</a></span></td><td class="int samples">4</td></tr><tr id="gds6100" onclick="javascript:Portal.$send('GDSRowClick', {'gds': 6100})" class="even"><td class="acc">GDS6100</td><td class="title"><div>MicroRNA-135b overexpression effect on prostate cancer cell line: time course</div></td><td class="species organism">Homo sapiens</td><td class="title-tt platform"><span title="Illumina HumanHT-12 V4.0 expression beadchip"><a href="/geo/query/acc.cgi?acc=GPL10558" target="_blank"> GPL10558</a></span></td><td class="title-tt series"><span title="The effect of miRNA-135b overexpression on the gene expression profile of LNCaP cells"><a href="/geo/query/acc.cgi?acc=GSE57820" target="_blank"> GSE57820</a></span></td><td class="int samples">12</td></tr><tr id="gds5660" onclick="javascript:Portal.$send('GDSRowClick', {'gds': 5660})"><td class="acc">GDS5660</td><td class="title"><div>Early postnatal skeletal muscle stem cells: time course</div></td><td class="species organism">Mus musculus</td><td class="title-tt platform"><span title="[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array"><a href="/geo/query/acc.cgi?acc=GPL1261" target="_blank"> GPL1261</a></span></td><td class="title-tt series"><span title="Early postnatal expression data from mouse skeletal muscle stem cells"><a href="/geo/query/acc.cgi?acc=GSE65927" target="_blank"> GSE65927</a></span></td><td class="int samples">11</td></tr><tr id="gds5624" onclick="javascript:Portal.$send('GDSRowClick', {'gds': 5624})" class="even"><td class="acc">GDS5624</td><td class="title"><div>Epigenetic modifying reagents effect on a progressive hearing loss model: whole cochlea</div></td><td class="species organism">Mus musculus</td><td class="title-tt platform"><span title="[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array"><a href="/geo/query/acc.cgi?acc=GPL1261" target="_blank"> GPL1261</a></span></td><td class="title-tt series"><span title="Expression data of mice cochlea treated with L-methionine and valproic acid."><a href="/geo/query/acc.cgi?acc=GSE62173" target="_blank"> GSE62173</a></span></td><td class="int samples">16</td></tr></table></div></div> <input type="hidden" name="p$a" id="p$a" /><input type="hidden" name="p$l" id="p$l" value="GDSBrowser_L" /><input type="hidden" name="p$st" id="p$st" value="GDSbrowser" /><input name="SessionId" id="SessionId" value="CE8B5AF87C7FFCB1_0191SID" disabled="disabled" type="hidden" /><input name="Snapshot" id="Snapshot" value="/projects/GEO/GDSBrowser@1.51" disabled="disabled" type="hidden" /></form> <div id="details"><table id="gds_details" class="gds_panel" summary="GEO DataSet Details"><tr class="caption"><th colspan="5"> DataSet Record GDS6063: <a href="/geoprofiles?term=GDS6063[ACCN]" target="_blank" class="button" title="View Expression Profiles"> Expression Profiles </a><a href="#details" class="button" onclick="displayAnalysis(6063); return true" title="Data Analysis Tools"> Data Analysis Tools </a><a href="#details" class="button" onclick="displaySamples(6063); return true" title="Sample Subsets"> Sample Subsets </a></th></tr><tr><th scope="row" class="not_caption"> Title: </th><td colspan="3">Influenza A effect on plasmacytoid dendritic cells</td><td id="detailsRightCol" rowspan="7"><fieldset><legend>Cluster Analysis</legend><a id="clusterLink" title="GDS6063 Cluster Analysis" href="/geo/gds/analyze/analyze.cgi?ID=GDS6063" target="_blank"><img alt="GDS6063 Cluster Image" width="80" height="80" src="/geo/img/UPGMA/UCorrelated/GDS6063i.png" /></a></fieldset><fieldset><legend>Download</legend><ul><li><a href="https://ftp.ncbi.nlm.nih.gov/geo/datasets/GDS6nnn/GDS6063/soft/GDS6063_full.soft.gz" title="Contains DataSet information, experiment variable subsets and expression value measurements (plain text, tab-delimited format)." class="dataset-soft-full"> DataSet full SOFT file </a></li><li><a href="https://ftp.ncbi.nlm.nih.gov/geo/datasets/GDS6nnn/GDS6063/soft/GDS6063.soft.gz" title="Contains DataSet information, experiment variable subsets, expression value measurements and up-to-date gene annotation for the DataSet Platform (plain text, tab-delimited format)." class="dataset-soft"> DataSet SOFT file </a></li><li><a href="https://ftp.ncbi.nlm.nih.gov/geo/series/GSE68nnn/GSE68849/soft/GSE68849_family.soft.gz" title="Contains the complete, original, submitter-supplied records that form the basis of this DataSet (plain text, tab-delimited format)." class="series-family-soft"> Series family SOFT file </a></li><li><a href="https://ftp.ncbi.nlm.nih.gov/geo/series/GSE68nnn/GSE68849/miniml/GSE68849_family.xml.tgz" title="Contains the complete, original, submitter-supplied records that form the basis of this DataSet (XML format)." class="series-family-miniml"> Series family MINiML file </a></li><li><a href="https://ftp.ncbi.nlm.nih.gov/geo/platforms/GPL10nnn/GPL10558/annot/GPL10558.annot.gz" title="Contains up-to-date gene annotation for the DataSet Platform (plain text, tab-delimited format)." class="annotation-soft"> Annotation SOFT file </a></li></ul></fieldset></td></tr><tr><th scope="row" class="not_caption"> Summary: </th><td colspan="3">Analysis of primary plasmacytoid dendritic cells (pDC) exposed to influenza A for 8 hours ex vivo. pDCs are vital to antiviral defense, directing immune responses via secretion of interferon-alpha. Results provide insight into the regulation of the response of pDC to viral pathogens.</td></tr><tr><th scope="row" class="not_caption">Organism: </th><td colspan="3" class="species"><a target="_blank" href="/Taxonomy/Browser/wwwtax.cgi?mode=Undef&lvl=0&srchmode=1&name=Homo%20sapiens">Homo sapiens</a></td></tr><tr><th scope="row" class="not_caption"> Platform: </th><td colspan="3"><a href="/geo/query/acc.cgi?acc=GPL10558" target="_blank"> GPL10558</a>: Illumina HumanHT-12 V4.0 expression beadchip</td></tr><tr><th scope="row" class="not_caption">Citation:</th><td colspan="3"><div class="PubmedCitation"><ul><li><span class="authors">Bajwa G, DeBerardinis RJ, Shao B, Hall B et al. </span><span class="title">Cutting Edge: Critical Role of Glycolysis in Human Plasmacytoid Dendritic Cell Antiviral Responses. </span><span class="source">J Immunol</span> 2016 Mar 1;196(5):2004-9. PMID: <a title="Link to PubMed record" href="https://www.ncbi.nlm.nih.gov/pubmed/26826244">26826244</a></li></ul></div></td></tr><tr><th scope="row" class="not_caption"> Reference Series: </th><td><a href="/geo/query/acc.cgi?acc=GSE68849" target="_blank"> GSE68849</a></td><th id="samp-cnt" class="not_caption"> Sample count: </th><td>10</td></tr><tr><th scope="row" class="not_caption"> Value type: </th><td>count</td><th id="series-pub" class="not_caption"> Series published: </th><td>2016/02/01</td></tr></table><div id="divExtra"></div></div> </div> <div id="footer"> <ul> <li class="first"><a href="https://www.nlm.nih.gov/">NLM</a></li> <li><a href="https://www.nih.gov/">NIH</a></li> <li><a href="mailto:geo@ncbi.nlm.nih.gov">GEO Help</a></li> <li><a href="/geo/info/disclaimer.html">Disclaimer</a></li> <li><a href="https://www.nlm.nih.gov/accessibility.html">Accessibility</a></li> </ul> </div> </div> <script type="text/javascript" src="/portal/portal3rc.fcgi/rlib/js/InstrumentOmnitureBaseJS/InstrumentNCBIBaseJS/InstrumentPageStarterJS.js"></script> <script type="text/javascript"> jQuery.getScript("/core/alerts/alerts.js", function () { galert(['div.nav_and_browser', 'div.header', '#universal_header', '#header']) }); </script> <!-- CE8B5AF87C7FFCB1_0191SID /projects/GEO/GDSBrowser@1.51 portal105 v4.1.r689238 Tue, Oct 22 2024 16:10:51 --> <span id="portal-csrf-token" style="display:none" data-token="CE8B5AF87C7FFCB1_0191SID"></span> <script type='text/javascript' src='/portal/js/portal.js'></script><script type="text/javascript" src="//static.pubmed.gov/portal/portal3rc.fcgi/4199987/js/4962/23410/4944/4093349/4807/3867120/3251151.js" snapshot="GDSbrowser"></script></body> </html>