Analysis of airway epithelial cells (AEC) from children with asthma and healthy non-atopic controls. Epithelial cells from asthmatic children fail to heal a wound in vitro. Results provide insight into the molecular mechanisms underlying dysregulated AEC repair.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Kicic A, Hallstrand TS, Sutanto EN, Stevens PT et al. Decreased fibronectin production significantly contributes to dysregulated repair of asthmatic epithelium. Am J Respir Crit Care Med 2010 May 1;181(9):889-98. PMID: 20110557