"PLoS Pathog"[jour] - PMC

Gonzalo R. Acevedo, Sophie S. Samiee, Mikias Ilala, Justine Levan, Meagan E. Olive, Riana D. Hunter, Mary Prahl, Raja Rajalingam, John Rek, Grant Dorsey, Margaret E. Feeney

PLoS Pathog. 2025 Feb; 21(2): e1012943. Published online 2025 Feb 24. doi: 10.1371/journal.ppat.1012943

PMCID:: PMC11906071

Article PDF–1.7M

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Citrus tristeza virus p20 suppresses antiviral RNA silencing by co-opting autophagy-related protein 8 to mediate the autophagic degradation of SGS3

Yongle Zhang, Zuokun Yang, Zhe Zhang, Guoping Wang, Xiang-Dong Li, Ni Hong

PLoS Pathog. 2025 Feb; 21(2): e1012960. Published online 2025 Feb 24. doi: 10.1371/journal.ppat.1012960

PMCID:: PMC11882097

Article PDF–5.1M

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A ribosome-interacting jumbophage protein associates with the phage nucleus to facilitate efficient propagation

Wichanan Wannasrichan, Sucheewin Krobthong, Chase J. Morgan, Emily G. Armbruster, Milan Gerovac, Yodying Yingchutrakul, Patompon Wongtrakoongate, Jörg Vogel, Chanat Aonbangkhen, Poochit Nonejuie, Joe Pogliano, Vorrapon Chaikeeratisak

PLoS Pathog. 2025 Feb; 21(2): e1012936. Published online 2025 Feb 24. doi: 10.1371/journal.ppat.1012936

PMCID:: PMC11849849

Article PDF–2.0M

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Mechanisms of resistance against allylamine and azole antifungals in Trichophyton: A renewed call for innovative molecular diagnostics in susceptibility testing

Aditya K. Gupta, Tong Wang, Avantika Mann, Vincent Piguet, Anuradha Chowdhary, Wayne L. Bakotic

PLoS Pathog. 2025 Feb; 21(2): e1012913. Published online 2025 Feb 11. doi: 10.1371/journal.ppat.1012913

PMCID:: PMC11813129

Article PDF–1.1M

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Repression of varicella zoster virus gene expression during quiescent infection in the absence of detectable histone deposition

Jiayi Wang, Nadine Brückner, Simon Weissmann, Thomas Günther, Shuyong Zhu, Carolin Vogt, Guorong Sun, Rongrong Guo, Renzo Bruno, Birgit Ritter, Lars Steinbrück, Benedikt B. Kaufer, Daniel P. Depledge, Adam Grundhoff, Abel Viejo-Borbolla

PLoS Pathog. 2025 Feb; 21(2): e1012367. Published online 2025 Feb 10. doi: 10.1371/journal.ppat.1012367

PMCID:: PMC11838886

Article PDF–3.1M

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E6AP is essential for the proliferation of HPV-positive cancer cells by preventing senescence

Alicia Avenhaus, Milica Velimirović, Julia Bulkescher, Martin Scheffner, Felix Hoppe-Seyler, Karin Hoppe-Seyler

PLoS Pathog. 2025 Feb; 21(2): e1012914. Published online 2025 Feb 7. doi: 10.1371/journal.ppat.1012914

PMCID:: PMC11805377

Article PDF–2.6M

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Host 3’ flap endonuclease Mus81 plays a critical role in trimming the terminal redundancy of hepatitis B virus relaxed circular DNA during covalently closed circular DNA formation

Hu Zhang, Quanxin Long, Yuanjie Liu, Alexander L. Marchetti, Cheng-Der Liu, Ning Sun, Haitao Guo

PLoS Pathog. 2025 Feb; 21(2): e1012918. Published online 2025 Feb 6. doi: 10.1371/journal.ppat.1012918

PMCID:: PMC11801639

Article PDF–4.8M

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Chromosomal genome assembly resolves drug resistance loci in the parasitic nematode Teladorsagia circumcincta

Jennifer McIntyre, Alison Morrison, Kirsty Maitland, Duncan Berger, Daniel R. G. Price, Sam Dougan, Dionysis Grigoriadis, Alan Tracey, Nancy Holroyd, Katie Bull, Hannah Rose Vineer, Mike J. Glover, Eric R. Morgan, Alasdair J. Nisbet, Tom N. McNeilly, Yvonne Bartley, Neil Sargison, Dave Bartley, Matt Berriman, James A. Cotton, Eileen Devaney, Roz Laing, Stephen R. Doyle

PLoS Pathog. 2025 Feb; 21(2): e1012820. Published online 2025 Feb 6. doi: 10.1371/journal.ppat.1012820

PMCID:: PMC11801625

Article PDF–2.9M

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Antibiotics change the population growth rate heterogeneity and morphology of bacteria

Morten Kals, Emma Kals, Jurij Kotar, Allen Donald, Leonardo Mancini, Pietro Cicuta

PLoS Pathog. 2025 Feb; 21(2): e1012924. Published online 2025 Feb 5. doi: 10.1371/journal.ppat.1012924

PMCID:: PMC11835381

Article PDF–3.3M

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A paradoxical population structure of var DBLα types in Africa

Mun Hua Tan, Kathryn E. Tiedje, Qian Feng, Qi Zhan, Mercedes Pascual, Heejung Shim, Yao-ban Chan, Karen P. Day

PLoS Pathog. 2025 Feb; 21(2): e1012813. Published online 2025 Feb 4. doi: 10.1371/journal.ppat.1012813

PMCID:: PMC11793742

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Streptococcus mutans regulates ubiquitin modification of Candida albicans in the bacterial-fungal interaction

Yixin Zhang, Zhen Gu, Zhengyi Li, Qinrui Wu, Xin Xu, Xian Peng

PLoS Pathog. 2025 Feb; 21(2): e1012887. Published online 2025 Feb 3. doi: 10.1371/journal.ppat.1012887

PMCID:: PMC11838896

Article PDF–3.7M

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Quinoxaline-based anti-schistosomal compounds have potent anti-plasmodial activity

Mukul Rawat, Gilda Padalino, Edem Adika, John Okombo, Tomas Yeo, Andrea Brancale, David A. Fidock, Karl F. Hoffmann, Marcus C. S. Lee

PLoS Pathog. 2025 Feb; 21(2): e1012216. Published online 2025 Feb 3. doi: 10.1371/journal.ppat.1012216

PMCID:: PMC11809919

Article PDF–2.1M

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Argonaute 2 targets viral transcripts but not genomes of RNA viruses during antiviral RNA interference in Drosophila

Emanuele G. Silva, Isaque J. S. de Faria, Álvaro G. A. Ferreira, Thiago Henrique L. Jiran, Carlos F. Estevez-Castro, Juliana N. Armache, Siad C. G. Amadou, Yann Verdier, Joëlle Vinh, Karim Majzoub, Carine Meignin, Gabrielle Haas, Franck Martin, Jean-Luc Imler, João T. Marques

PLoS Pathog. 2025 Feb; 21(2): e1012184. Published online 2025 Feb 3. doi: 10.1371/journal.ppat.1012184

PMCID:: PMC11809787

Article PDF–1.2M

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Decoding Cryptococcus: From African biodiversity to worldwide prevalence

Marco A. Coelho, Márcia David-Palma, Janneke Aylward, Nam Q. Pham, Cobus M. Visagie, Taygen Fuchs, Neriman Yilmaz, Francois Roets, Sheng Sun, John W. Taylor, Brenda D. Wingfield, Matthew C. Fisher, Michael J. Wingfield, Joseph Heitman

PLoS Pathog. 2025 Feb; 21(2): e1012876. Published online 2025 Feb 3. doi: 10.1371/journal.ppat.1012876

PMCID:: PMC11790112

Article PDF–830K

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Marek’s disease virus-1 unique gene LORF1 is involved in viral replication and MDV-1/Md5-induced atrophy of the bursa of Fabricius

Chenyi Bao, Jun Chu, Qi Gao, Shasha Yang, Xiaoyu Gao, Wenwen Chen, Fuchun Yang, Fei Jiang, Chenxi Tong, Mingyi Lei, Linlin Jiao, Jitong Li, Kexin Wei, Xue Lian, Kai Li, Suresh Kumar Tikoo, Nikolaus Osterrieder, Lorne A. Babiuk, Yufeng Li, Yong-Sam Jung, Yingjuan Qian

PLoS Pathog. 2025 Feb; 21(2): e1012891. Published online 2025 Feb 3. doi: 10.1371/journal.ppat.1012891