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Ventricular tachycardia, catecholaminergic polymorphic 6(CPVT6)

MedGen UID:
1712279
Concept ID:
C5394069
Disease or Syndrome
Synonyms: CPVT6; VENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC 6; VENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 6
 
Monarch Initiative: MONDO:0800374
OMIM®: 114183; 618782

Professional guidelines

PubMed

Specterman MJ, Behr ER
Heart 2023 Feb 23;109(6):434-441. doi: 10.1136/heartjnl-2021-320015. PMID: 36167638
Claudio B, Alice M, Daniel S
Mini Rev Med Chem 2018;18(6):476-482. doi: 10.2174/1389557517666170707100923. PMID: 28685702
Wilde AA, van der Werf C
J Electrocardiol 2012 Nov-Dec;45(6):739-40. Epub 2012 Jul 25 doi: 10.1016/j.jelectrocard.2012.06.027. PMID: 22840921

Recent clinical studies

Etiology

Stevens TL, Coles S, Sturm AC, Hoover CA, Borzok MA, Mohler PJ, El Refaey M
Adv Exp Med Biol 2024;1441:1057-1090. doi: 10.1007/978-3-031-44087-8_67. PMID: 38884769
Mazzanti A, Kukavica D, Trancuccio A, Memmi M, Bloise R, Gambelli P, Marino M, Ortíz-Genga M, Morini M, Monteforte N, Giordano U, Keegan R, Tomasi L, Anastasakis A, Davis AM, Shimizu W, Blom NA, Santiago DJ, Napolitano C, Monserrat L, Priori SG
JAMA Cardiol 2022 May 1;7(5):504-512. doi: 10.1001/jamacardio.2022.0219. PMID: 35353122Free PMC Article
Schwartz PJ, Ackerman MJ, Antzelevitch C, Bezzina CR, Borggrefe M, Cuneo BF, Wilde AAM
Nat Rev Dis Primers 2020 Jul 16;6(1):58. doi: 10.1038/s41572-020-0188-7. PMID: 32678103Free PMC Article
Wall JJ, Iyer RV
Pediatr Emerg Care 2017 Jun;33(6):427-431. doi: 10.1097/PEC.0000000000001156. PMID: 28570361
Priori SG, Cerrone M
Ital Heart J 2005 Mar;6(3):241-8. PMID: 15875515

Diagnosis

Krahn AD, Tfelt-Hansen J, Tadros R, Steinberg C, Semsarian C, Han HC
JACC Clin Electrophysiol 2022 Jun;8(6):806-821. doi: 10.1016/j.jacep.2021.12.014. PMID: 35738861
Mazzanti A, Kukavica D, Trancuccio A, Memmi M, Bloise R, Gambelli P, Marino M, Ortíz-Genga M, Morini M, Monteforte N, Giordano U, Keegan R, Tomasi L, Anastasakis A, Davis AM, Shimizu W, Blom NA, Santiago DJ, Napolitano C, Monserrat L, Priori SG
JAMA Cardiol 2022 May 1;7(5):504-512. doi: 10.1001/jamacardio.2022.0219. PMID: 35353122Free PMC Article
Watkins K, Gelber J, Kaushik N, Shaahinfar A
Ann Emerg Med 2021 Jun;77(6):597-600. doi: 10.1016/j.annemergmed.2020.10.002. PMID: 34030774
Schwartz PJ, Ackerman MJ, Antzelevitch C, Bezzina CR, Borggrefe M, Cuneo BF, Wilde AAM
Nat Rev Dis Primers 2020 Jul 16;6(1):58. doi: 10.1038/s41572-020-0188-7. PMID: 32678103Free PMC Article
Nat Rev Dis Primers 2020 Jul 16;6(1):59. doi: 10.1038/s41572-020-0202-0. PMID: 32678096

Therapy

Shen L, Liu S, Hu F, Zhang Z, Li J, Lai Z, Zheng L, Yao Y
J Am Heart Assoc 2023 Dec 19;12(24):e031768. Epub 2023 Dec 8 doi: 10.1161/JAHA.123.031768. PMID: 38063176Free PMC Article
Mazzanti A, Kukavica D, Trancuccio A, Memmi M, Bloise R, Gambelli P, Marino M, Ortíz-Genga M, Morini M, Monteforte N, Giordano U, Keegan R, Tomasi L, Anastasakis A, Davis AM, Shimizu W, Blom NA, Santiago DJ, Napolitano C, Monserrat L, Priori SG
JAMA Cardiol 2022 May 1;7(5):504-512. doi: 10.1001/jamacardio.2022.0219. PMID: 35353122Free PMC Article
Claudio B, Alice M, Daniel S
Mini Rev Med Chem 2018;18(6):476-482. doi: 10.2174/1389557517666170707100923. PMID: 28685702
Wall JJ, Iyer RV
Pediatr Emerg Care 2017 Jun;33(6):427-431. doi: 10.1097/PEC.0000000000001156. PMID: 28570361
Faggioni M, Knollmann BC
Am J Physiol Heart Circ Physiol 2012 Mar 15;302(6):H1250-60. Epub 2011 Dec 23 doi: 10.1152/ajpheart.00779.2011. PMID: 22198169Free PMC Article

Prognosis

Yan Y, Tang L, Wang X, Zhou K, Hu F, Duan H, Liu X, Hua Y, Wang C
Orphanet J Rare Dis 2023 Dec 5;18(1):380. doi: 10.1186/s13023-023-02991-0. PMID: 38053087Free PMC Article
Bergeman AT, Lieve KVV, Kallas D, Bos JM, Rosés I Noguer F, Denjoy I, Zorio E, Kammeraad JAE, Peltenburg PJ, Tobert K, Aiba T, Atallah J, Drago F, Batra AS, Brugada R, Borggrefe M, Clur SB, Cox MGPJ, Davis A, Dhillon S, Etheridge SP, Fischbach P, Franciosi S, Haugaa K, Horie M, Johnsrude C, Kane AM, Krause U, Kwok SY, LaPage MJ, Ohno S, Probst V, Roberts JD, Robyns T, Sacher F, Semsarian C, Skinner JR, Swan H, Tavacova T, Tisma-Dupanovic S, Tfelt-Hansen J, Yap SC, Kannankeril PJ, Leenhardt A, Till J, Sanatani S, Tanck MWT, Ackerman MJ, Wilde AAM, van der Werf C
Circulation 2023 Dec 19;148(25):2029-2037. Epub 2023 Oct 27 doi: 10.1161/CIRCULATIONAHA.123.064786. PMID: 37886885Free PMC Article
Specterman MJ, Behr ER
Heart 2023 Feb 23;109(6):434-441. doi: 10.1136/heartjnl-2021-320015. PMID: 36167638
Michowitz Y, Viskin S, Rosso R
Card Electrophysiol Clin 2016 Sep;8(3):593-600. Epub 2016 Jun 18 doi: 10.1016/j.ccep.2016.04.008. PMID: 27521092
Obeyesekere MN, Klein GJ, Modi S, Leong-Sit P, Gula LJ, Yee R, Skanes AC, Krahn AD
Circ Arrhythm Electrophysiol 2011 Dec;4(6):958-64. doi: 10.1161/CIRCEP.111.965947. PMID: 22203660

Clinical prediction guides

Shen L, Liu S, Hu F, Zhang Z, Li J, Lai Z, Zheng L, Yao Y
J Am Heart Assoc 2023 Dec 19;12(24):e031768. Epub 2023 Dec 8 doi: 10.1161/JAHA.123.031768. PMID: 38063176Free PMC Article
Specterman MJ, Behr ER
Heart 2023 Feb 23;109(6):434-441. doi: 10.1136/heartjnl-2021-320015. PMID: 36167638
Roston TM, Wei J, Guo W, Li Y, Zhong X, Wang R, Estillore JP, Peltenburg PJ, Noguer FRI, Till J, Eckhardt LL, Orland KM, Hamilton R, LaPage MJ, Krahn AD, Tadros R, Vinocur JM, Kallas D, Franciosi S, Roberts JD, Wilde AAM, Jensen HK, Sanatani S, Chen SRW
JAMA Cardiol 2022 Jan 1;7(1):84-92. doi: 10.1001/jamacardio.2021.4458. PMID: 34730774Free PMC Article
Roston TM, Jones K, Hawkins NM, Bos JM, Schwartz PJ, Perry F, Ackerman MJ, Laksman ZWM, Kaul P, Lieve KVV, Atallah J, Krahn AD, Sanatani S
Heart Rhythm 2018 Dec;15(12):1791-1799. Epub 2018 Jul 3 doi: 10.1016/j.hrthm.2018.06.046. PMID: 30063211
Obeyesekere MN, Klein GJ, Modi S, Leong-Sit P, Gula LJ, Yee R, Skanes AC, Krahn AD
Circ Arrhythm Electrophysiol 2011 Dec;4(6):958-64. doi: 10.1161/CIRCEP.111.965947. PMID: 22203660

Recent systematic reviews

Lawley CM, Tester M, Sanatani S, Prendiville T, Beach CM, Vinocur JM, Horie M, Uhm JS, Khongphatthanayothin A, Ayers MD, Starling L, Yoshida Y, Shah MJ, Skinner JR, Turner C
Heart Rhythm 2022 Nov;19(11):1826-1833. Epub 2022 Oct 11 doi: 10.1016/j.hrthm.2022.08.003. PMID: 37850595
Sgrò A, Drake TM, Lopez-Ayala P, Phan K
Congenit Heart Dis 2019 Nov;14(6):1102-1112. Epub 2019 Oct 16 doi: 10.1111/chd.12855. PMID: 31621201
Roston TM, Jones K, Hawkins NM, Bos JM, Schwartz PJ, Perry F, Ackerman MJ, Laksman ZWM, Kaul P, Lieve KVV, Atallah J, Krahn AD, Sanatani S
Heart Rhythm 2018 Dec;15(12):1791-1799. Epub 2018 Jul 3 doi: 10.1016/j.hrthm.2018.06.046. PMID: 30063211
McNamara DA, Goldberger JJ, Berendsen MA, Huffman MD
Cochrane Database Syst Rev 2015 Oct 7;2015(10):CD011168. doi: 10.1002/14651858.CD011168.pub2. PMID: 26445202Free PMC Article
Clausen H, Pflaumer A, Kamberi S, Davis A
Pacing Clin Electrophysiol 2013 Mar;36(3):391-401. Epub 2012 Dec 18 doi: 10.1111/pace.12050. PMID: 23252797

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