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Susceptibility to hangover

MedGen UID:
382016
•Concept ID:
C2608086
•
Finding
Synonym: HANGOVER, SUSCEPTIBILITY TO
 
OMIM®: 100650; 610251

Professional guidelines

PubMed

Hangover susceptibility in relation to aldehyde dehydrogenase-2 genotype, alcohol flushing, and mean corpuscular volume in Japanese workers.
Yokoyama M, Yokoyama A, Yokoyama T, Funazu K, Hamana G, Kondo S, Yamashita T, Nakamura H
Alcohol Clin Exp Res 2005 Jul;29(7):1165-71. doi: 10.1097/01.alc.0000172457.62535.ee. PMID: 16046871

Recent clinical studies

Etiology

Gender Differences in the Epidemiology of Alcohol Use and Related Harms in the United States.
White AM
Alcohol Res 2020;40(2):01. Epub 2020 Oct 29 doi: 10.35946/arcr.v40.2.01. PMID: 33133878Free PMC Article
Hangover Symptoms, Heavy Episodic Drinking, and Depression in Young Adults: A Cross-Lagged Analysis.
Piasecki TM, Trela CJ, Mermelstein RJ
J Stud Alcohol Drugs 2017 Jul;78(4):580-587. doi: 10.15288/jsad.2017.78.580. PMID: 28728640Free PMC Article
Genetic influences on alcohol-related hangover.
Slutske WS, Piasecki TM, Nathanson L, Statham DJ, Martin NG
Addiction 2014 Dec;109(12):2027-34. Epub 2014 Sep 10 doi: 10.1111/add.12699. PMID: 25098862Free PMC Article
Low sensitivity to alcohol: relations with hangover occurrence and susceptibility in an ecological momentary assessment investigation.
Piasecki TM, Alley KJ, Slutske WS, Wood PK, Sher KJ, Shiffman S, Heath AC
J Stud Alcohol Drugs 2012 Nov;73(6):925-32. doi: 10.15288/jsad.2012.73.925. PMID: 23036210Free PMC Article
Hangover and risk for alcohol use disorders: existing evidence and potential mechanisms.
Piasecki TM, Robertson BM, Epler AJ
Curr Drug Abuse Rev 2010 Jun;3(2):92-102. doi: 10.2174/1874473711003020092. PMID: 20712598Free PMC Article

Diagnosis

Susceptibility to Alcohol Hangovers: Not Just a Matter of Being Resilient.
van Schrojenstein Lantman M, van de Loo AJAE, Mackus M, Kraneveld AD, Brookhuis KA, Garssen J, Verster JC
Alcohol Alcohol 2018 May 1;53(3):241-244. doi: 10.1093/alcalc/agx107. PMID: 29211818
Low sensitivity to alcohol: relations with hangover occurrence and susceptibility in an ecological momentary assessment investigation.
Piasecki TM, Alley KJ, Slutske WS, Wood PK, Sher KJ, Shiffman S, Heath AC
J Stud Alcohol Drugs 2012 Nov;73(6):925-32. doi: 10.15288/jsad.2012.73.925. PMID: 23036210Free PMC Article
Interactions between migraine and tension-type headache and alcohol drinking, alcohol flushing, and hangover in Japanese.
Yokoyama M, Suzuki N, Yokoyama T, Yokoyama A, Funazu K, Shimizu T, Shibata M
J Headache Pain 2012 Mar;13(2):137-45. Epub 2012 Jan 11 doi: 10.1007/s10194-011-0413-6. PMID: 22234728Free PMC Article
Alcohol dependence is associated with the ZNF699 gene, a human locus related to Drosophila hangover, in the Irish Affected Sib Pair Study of Alcohol Dependence (IASPSAD) sample.
Riley BP, Kalsi G, Kuo PH, Vladimirov V, Thiselton DL, Vittum J, Wormley B, Grotewiel MS, Patterson DG, Sullivan PF, van den Oord E, Walsh D, Kendler KS, Prescott CA
Mol Psychiatry 2006 Nov;11(11):1025-31. Epub 2006 Aug 29 doi: 10.1038/sj.mp.4001891. PMID: 16940975
Genetic associations of alcohol dehydrogenase with alcohol use disorders and endophenotypes in white college students.
Wall TL, Shea SH, Luczak SE, Cook TA, Carr LG
J Abnorm Psychol 2005 Aug;114(3):456-65. doi: 10.1037/0021-843X.114.3.456. PMID: 16117582

Therapy

Daily experiences of hangover severity and food consumption in young adults.
Morley KC, Logge WB, Riordan BC, Brannon S, Haber PS, Conner TS
Br J Health Psychol 2022 May;27(2):468-483. Epub 2021 Aug 25 doi: 10.1111/bjhp.12555. PMID: 34431182
The use of N-acetylcysteine in the prevention of hangover: a randomized trial.
Coppersmith V, Hudgins S, Stoltzfus J, Stankewicz H
Sci Rep 2021 Jun 28;11(1):13397. doi: 10.1038/s41598-021-92676-0. PMID: 34183702Free PMC Article
Genetic influences on alcohol-related hangover.
Slutske WS, Piasecki TM, Nathanson L, Statham DJ, Martin NG
Addiction 2014 Dec;109(12):2027-34. Epub 2014 Sep 10 doi: 10.1111/add.12699. PMID: 25098862Free PMC Article
Low sensitivity to alcohol: relations with hangover occurrence and susceptibility in an ecological momentary assessment investigation.
Piasecki TM, Alley KJ, Slutske WS, Wood PK, Sher KJ, Shiffman S, Heath AC
J Stud Alcohol Drugs 2012 Nov;73(6):925-32. doi: 10.15288/jsad.2012.73.925. PMID: 23036210Free PMC Article
Hangover and risk for alcohol use disorders: existing evidence and potential mechanisms.
Piasecki TM, Robertson BM, Epler AJ
Curr Drug Abuse Rev 2010 Jun;3(2):92-102. doi: 10.2174/1874473711003020092. PMID: 20712598Free PMC Article

Prognosis

Elucidating the alcohol-sleep-hangover relationship in college students using a daily diary approach.
Muzumdar N, Jackson KM, Buckman JF, Spaeth AM, Sokolovsky AW, Pawlak AP, White HR
Pharmacol Biochem Behav 2025 Feb;247:173910. Epub 2024 Nov 21 doi: 10.1016/j.pbb.2024.173910. PMID: 39579876
Daily experiences of hangover severity and food consumption in young adults.
Morley KC, Logge WB, Riordan BC, Brannon S, Haber PS, Conner TS
Br J Health Psychol 2022 May;27(2):468-483. Epub 2021 Aug 25 doi: 10.1111/bjhp.12555. PMID: 34431182
The effects of alcohol hangover on future drinking behavior and the development of alcohol problems.
Courtney KE, Worley M, Castro N, Tapert SF
Addict Behav 2018 Mar;78:209-215. Epub 2017 Nov 28 doi: 10.1016/j.addbeh.2017.11.040. PMID: 29216570Free PMC Article
Hangover Symptoms, Heavy Episodic Drinking, and Depression in Young Adults: A Cross-Lagged Analysis.
Piasecki TM, Trela CJ, Mermelstein RJ
J Stud Alcohol Drugs 2017 Jul;78(4):580-587. doi: 10.15288/jsad.2017.78.580. PMID: 28728640Free PMC Article
Low sensitivity to alcohol: relations with hangover occurrence and susceptibility in an ecological momentary assessment investigation.
Piasecki TM, Alley KJ, Slutske WS, Wood PK, Sher KJ, Shiffman S, Heath AC
J Stud Alcohol Drugs 2012 Nov;73(6):925-32. doi: 10.15288/jsad.2012.73.925. PMID: 23036210Free PMC Article

Clinical prediction guides

Daily experiences of hangover severity and food consumption in young adults.
Morley KC, Logge WB, Riordan BC, Brannon S, Haber PS, Conner TS
Br J Health Psychol 2022 May;27(2):468-483. Epub 2021 Aug 25 doi: 10.1111/bjhp.12555. PMID: 34431182
The use of N-acetylcysteine in the prevention of hangover: a randomized trial.
Coppersmith V, Hudgins S, Stoltzfus J, Stankewicz H
Sci Rep 2021 Jun 28;11(1):13397. doi: 10.1038/s41598-021-92676-0. PMID: 34183702Free PMC Article
Susceptibility to Alcohol Hangovers: The Association with Self-Reported Immune Status.
van de Loo AJAE, Mackus M, van Schrojenstein Lantman M, Kraneveld AD, Brookhuis KA, Garssen J, Scholey A, Verster JC
Int J Environ Res Public Health 2018 Jun 18;15(6) doi: 10.3390/ijerph15061286. PMID: 29912152Free PMC Article
Hangover Symptoms, Heavy Episodic Drinking, and Depression in Young Adults: A Cross-Lagged Analysis.
Piasecki TM, Trela CJ, Mermelstein RJ
J Stud Alcohol Drugs 2017 Jul;78(4):580-587. doi: 10.15288/jsad.2017.78.580. PMID: 28728640Free PMC Article
Low sensitivity to alcohol: relations with hangover occurrence and susceptibility in an ecological momentary assessment investigation.
Piasecki TM, Alley KJ, Slutske WS, Wood PK, Sher KJ, Shiffman S, Heath AC
J Stud Alcohol Drugs 2012 Nov;73(6):925-32. doi: 10.15288/jsad.2012.73.925. PMID: 23036210Free PMC Article

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