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LACTASE PERSISTENCE

MedGen UID:
347396
Concept ID:
C1857231
Finding
OMIM®: 223100; 601806

Professional guidelines

PubMed

Anguita-Ruiz A, Aguilera CM, Gil Á
Nutrients 2020 Sep 3;12(9) doi: 10.3390/nu12092689. PMID: 32899182Free PMC Article
Misselwitz B, Butter M, Verbeke K, Fox MR
Gut 2019 Nov;68(11):2080-2091. Epub 2019 Aug 19 doi: 10.1136/gutjnl-2019-318404. PMID: 31427404Free PMC Article
Di Rienzo T, D'Angelo G, D'Aversa F, Campanale MC, Cesario V, Montalto M, Gasbarrini A, Ojetti V
Eur Rev Med Pharmacol Sci 2013;17 Suppl 2:18-25. PMID: 24443063

Recent clinical studies

Etiology

Carlberg C
Redox Biol 2023 Jun;62:102656. Epub 2023 Mar 11 doi: 10.1016/j.redox.2023.102656. PMID: 36933390Free PMC Article
Qi Q, Li J, Yu B, Moon JY, Chai JC, Merino J, Hu J, Ruiz-Canela M, Rebholz C, Wang Z, Usyk M, Chen GC, Porneala BC, Wang W, Nguyen NQ, Feofanova EV, Grove ML, Wang TJ, Gerszten RE, Dupuis J, Salas-Salvadó J, Bao W, Perkins DL, Daviglus ML, Thyagarajan B, Cai J, Wang T, Manson JE, Martínez-González MA, Selvin E, Rexrode KM, Clish CB, Hu FB, Meigs JB, Knight R, Burk RD, Boerwinkle E, Kaplan RC
Gut 2022 Jun;71(6):1095-1105. Epub 2021 Jun 14 doi: 10.1136/gutjnl-2021-324053. PMID: 34127525Free PMC Article
Bleasdale M, Richter KK, Janzen A, Brown S, Scott A, Zech J, Wilkin S, Wang K, Schiffels S, Desideri J, Besse M, Reinold J, Saad M, Babiker H, Power RC, Ndiema E, Ogola C, Manthi FK, Zahir M, Petraglia M, Trachsel C, Nanni P, Grossmann J, Hendy J, Crowther A, Roberts P, Goldstein ST, Boivin N
Nat Commun 2021 Jan 27;12(1):632. doi: 10.1038/s41467-020-20682-3. PMID: 33504791Free PMC Article
Misselwitz B, Butter M, Verbeke K, Fox MR
Gut 2019 Nov;68(11):2080-2091. Epub 2019 Aug 19 doi: 10.1136/gutjnl-2019-318404. PMID: 31427404Free PMC Article
Storhaug CL, Fosse SK, Fadnes LT
Lancet Gastroenterol Hepatol 2017 Oct;2(10):738-746. Epub 2017 Jul 7 doi: 10.1016/S2468-1253(17)30154-1. PMID: 28690131

Diagnosis

Černý V, Fortes-Lima C, Tříska P
Hum Mol Genet 2021 Apr 26;30(R1):R29-R36. doi: 10.1093/hmg/ddaa239. PMID: 33105478
Misselwitz B, Butter M, Verbeke K, Fox MR
Gut 2019 Nov;68(11):2080-2091. Epub 2019 Aug 19 doi: 10.1136/gutjnl-2019-318404. PMID: 31427404Free PMC Article
Storhaug CL, Fosse SK, Fadnes LT
Lancet Gastroenterol Hepatol 2017 Oct;2(10):738-746. Epub 2017 Jul 7 doi: 10.1016/S2468-1253(17)30154-1. PMID: 28690131
Cramp LJ, Evershed RP, Lavento M, Halinen P, Mannermaa K, Oinonen M, Kettunen J, Perola M, Onkamo P, Heyd V
Proc Biol Sci 2014 Sep 22;281(1791):20140819. doi: 10.1098/rspb.2014.0819. PMID: 25080345Free PMC Article
Di Rienzo T, D'Angelo G, D'Aversa F, Campanale MC, Cesario V, Montalto M, Gasbarrini A, Ojetti V
Eur Rev Med Pharmacol Sci 2013;17 Suppl 2:18-25. PMID: 24443063

Therapy

Vissers LET, Sluijs I, Burgess S, Forouhi NG, Freisling H, Imamura F, Nilsson TK, Renström F, Weiderpass E, Aleksandrova K, Dahm CC, Perez-Cornago A, Schulze MB, Tong TYN, Aune D, Bonet C, Boer JMA, Boeing H, Chirlaque MD, Conchi MI, Imaz L, Jäger S, Krogh V, Kyrø C, Masala G, Melander O, Overvad K, Panico S, Sánches MJ, Sonestedt E, Tjønneland A, Tzoulaki I, Verschuren WMM, Riboli E, Wareham NJ, Danesh J, Butterworth AS, van der Schouw YT
Br J Nutr 2022 Nov 14;128(9):1789-1797. Epub 2021 Oct 21 doi: 10.1017/S0007114521004244. PMID: 34670632Free PMC Article
Ding M, Huang T, Bergholdt HK, Nordestgaard BG, Ellervik C, Qi L; CHARGE Consortium
BMJ 2017 Mar 16;356:j1000. doi: 10.1136/bmj.j1000. PMID: 28302601Free PMC Article
Wahlqvist ML
Asia Pac J Clin Nutr 2015;24 Suppl 1:S21-5. doi: 10.6133/apjcn.2015.24.s1.04. PMID: 26715080
Di Rienzo T, D'Angelo G, D'Aversa F, Campanale MC, Cesario V, Montalto M, Gasbarrini A, Ojetti V
Eur Rev Med Pharmacol Sci 2013;17 Suppl 2:18-25. PMID: 24443063
Meloni GF, Colombo C, La Vecchia C, Ruggiu G, Mannazzu MC, Ambrosini G, Cherchi PL
Am J Epidemiol 1999 Jul 15;150(2):183-6. doi: 10.1093/oxfordjournals.aje.a009978. PMID: 10412963

Prognosis

Kaufman EJ, Tan C
Sociol Health Illn 2022 Nov;44(9):1533-1550. Epub 2022 Aug 26 doi: 10.1111/1467-9566.13528. PMID: 36018892
Vissers LET, Sluijs I, Burgess S, Forouhi NG, Freisling H, Imamura F, Nilsson TK, Renström F, Weiderpass E, Aleksandrova K, Dahm CC, Perez-Cornago A, Schulze MB, Tong TYN, Aune D, Bonet C, Boer JMA, Boeing H, Chirlaque MD, Conchi MI, Imaz L, Jäger S, Krogh V, Kyrø C, Masala G, Melander O, Overvad K, Panico S, Sánches MJ, Sonestedt E, Tjønneland A, Tzoulaki I, Verschuren WMM, Riboli E, Wareham NJ, Danesh J, Butterworth AS, van der Schouw YT
Br J Nutr 2022 Nov 14;128(9):1789-1797. Epub 2021 Oct 21 doi: 10.1017/S0007114521004244. PMID: 34670632Free PMC Article
Amiri M, Diekmann L, von Köckritz-Blickwede M, Naim HY
Nutrients 2015 Aug 28;7(9):7209-30. doi: 10.3390/nu7095332. PMID: 26343715Free PMC Article
Di Rienzo T, D'Angelo G, D'Aversa F, Campanale MC, Cesario V, Montalto M, Gasbarrini A, Ojetti V
Eur Rev Med Pharmacol Sci 2013;17 Suppl 2:18-25. PMID: 24443063
Mattar R, Monteiro Mdo S, Silva JM, Carrilho FJ
Clinics (Sao Paulo) 2010;65(12):1399. doi: 10.1590/s1807-59322010001200030. PMID: 21340236Free PMC Article

Clinical prediction guides

Irving-Pease EK, Refoyo-Martínez A, Barrie W, Ingason A, Pearson A, Fischer A, Sjögren KG, Halgren AS, Macleod R, Demeter F, Henriksen RA, Vimala T, McColl H, Vaughn AH, Speidel L, Stern AJ, Scorrano G, Ramsøe A, Schork AJ, Rosengren A, Zhao L, Kristiansen K, Iversen AKN, Fugger L, Sudmant PH, Lawson DJ, Durbin R, Korneliussen T, Werge T, Allentoft ME, Sikora M, Nielsen R, Racimo F, Willerslev E
Nature 2024 Jan;625(7994):312-320. Epub 2024 Jan 10 doi: 10.1038/s41586-023-06705-1. PMID: 38200293Free PMC Article
Vissers LET, Sluijs I, Burgess S, Forouhi NG, Freisling H, Imamura F, Nilsson TK, Renström F, Weiderpass E, Aleksandrova K, Dahm CC, Perez-Cornago A, Schulze MB, Tong TYN, Aune D, Bonet C, Boer JMA, Boeing H, Chirlaque MD, Conchi MI, Imaz L, Jäger S, Krogh V, Kyrø C, Masala G, Melander O, Overvad K, Panico S, Sánches MJ, Sonestedt E, Tjønneland A, Tzoulaki I, Verschuren WMM, Riboli E, Wareham NJ, Danesh J, Butterworth AS, van der Schouw YT
Br J Nutr 2022 Nov 14;128(9):1789-1797. Epub 2021 Oct 21 doi: 10.1017/S0007114521004244. PMID: 34670632Free PMC Article
Černý V, Kulichová I, Poloni ES, Nunes JM, Pereira L, Mayor A, Sanchez-Mazas A
HLA 2018 Mar;91(3):153-166. Epub 2018 Jan 16 doi: 10.1111/tan.13189. PMID: 29215793
Storhaug CL, Fosse SK, Fadnes LT
Lancet Gastroenterol Hepatol 2017 Oct;2(10):738-746. Epub 2017 Jul 7 doi: 10.1016/S2468-1253(17)30154-1. PMID: 28690131
Di Rienzo T, D'Angelo G, D'Aversa F, Campanale MC, Cesario V, Montalto M, Gasbarrini A, Ojetti V
Eur Rev Med Pharmacol Sci 2013;17 Suppl 2:18-25. PMID: 24443063

Recent systematic reviews

Storhaug CL, Fosse SK, Fadnes LT
Lancet Gastroenterol Hepatol 2017 Oct;2(10):738-746. Epub 2017 Jul 7 doi: 10.1016/S2468-1253(17)30154-1. PMID: 28690131
Ding M, Huang T, Bergholdt HK, Nordestgaard BG, Ellervik C, Qi L; CHARGE Consortium
BMJ 2017 Mar 16;356:j1000. doi: 10.1136/bmj.j1000. PMID: 28302601Free PMC Article
Hartwig FP, Horta BL, Smith GD, de Mola CL, Victora CG
Int J Epidemiol 2016 Oct;45(5):1573-1587. Epub 2016 May 11 doi: 10.1093/ije/dyw074. PMID: 27170764Free PMC Article

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