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Thrombus

MedGen UID:
43439
Concept ID:
C0087086
Pathologic Function
Synonyms: Blood Clot; Blood Clots
SNOMED CT: Thrombus (396339007)

Professional guidelines

PubMed

Saposnik G, Bushnell C, Coutinho JM, Field TS, Furie KL, Galadanci N, Kam W, Kirkham FC, McNair ND, Singhal AB, Thijs V, Yang VXD; American Heart Association Stroke Council; Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation; Council on Cardiovascular and Stroke Nursing; and Council on Hypertension
Stroke 2024 Mar;55(3):e77-e90. Epub 2024 Jan 29 doi: 10.1161/STR.0000000000000456. PMID: 38284265
Alkhouli M, Alarouri H, Kramer A, Korsholm K, Collins J, De Backer O, Hatoum H, Nielsen-Kudsk JE
JACC Cardiovasc Interv 2023 Nov 27;16(22):2695-2707. doi: 10.1016/j.jcin.2023.10.046. PMID: 38030357
Yoshiji H, Nagoshi S, Akahane T, Asaoka Y, Ueno Y, Ogawa K, Kawaguchi T, Kurosaki M, Sakaida I, Shimizu M, Taniai M, Terai S, Nishikawa H, Hiasa Y, Hidaka H, Miwa H, Chayama K, Enomoto N, Shimosegawa T, Takehara T, Koike K
J Gastroenterol 2021 Jul;56(7):593-619. Epub 2021 Jul 7 doi: 10.1007/s00535-021-01788-x. PMID: 34231046Free PMC Article

Recent clinical studies

Etiology

Yan C, Li H, Wang C, Yu H, Guo T, Wan L, Yundan P, Wang L, Fang W
Stroke 2023 May;54(5):1205-1213. Epub 2023 Mar 9 doi: 10.1161/STROKEAHA.122.041524. PMID: 36891906
Goyal SK, Hyder S, Liu S, Vannan MA
JACC Clin Electrophysiol 2023 Jan;9(1):111-116. Epub 2022 Nov 30 doi: 10.1016/j.jacep.2022.10.026. PMID: 36697189
Levine GN, McEvoy JW, Fang JC, Ibeh C, McCarthy CP, Misra A, Shah ZI, Shenoy C, Spinler SA, Vallurupalli S, Lip GYH; American Heart Association Council on Clinical Cardiology; Council on Cardiovascular and Stroke Nursing; and Stroke Council
Circulation 2022 Oct 11;146(15):e205-e223. Epub 2022 Sep 15 doi: 10.1161/CIR.0000000000001092. PMID: 36106537
Honan KA, Jogimahanti A, Khair T
Am J Med 2022 Jan;135(1):17-23. Epub 2021 Aug 29 doi: 10.1016/j.amjmed.2021.07.023. PMID: 34469758
Kirresh A, Coghlan G, Candilio L
Cardiovasc Revasc Med 2021 Jul;28:82-87. Epub 2020 Jul 30 doi: 10.1016/j.carrev.2020.07.032. PMID: 32967797Free PMC Article

Diagnosis

Levine GN, McEvoy JW, Fang JC, Ibeh C, McCarthy CP, Misra A, Shah ZI, Shenoy C, Spinler SA, Vallurupalli S, Lip GYH; American Heart Association Council on Clinical Cardiology; Council on Cardiovascular and Stroke Nursing; and Stroke Council
Circulation 2022 Oct 11;146(15):e205-e223. Epub 2022 Sep 15 doi: 10.1161/CIR.0000000000001092. PMID: 36106537
Kumar V, Sharma AK, Kumar T, Nath RK
Indian Heart J 2020 Nov-Dec;72(6):508-516. Epub 2020 Nov 19 doi: 10.1016/j.ihj.2020.11.009. PMID: 33357638Free PMC Article
Sereni CP, Rodgers SK, Kirby CL, Goykhman I
Abdom Radiol (NY) 2017 Jan;42(1):159-170. doi: 10.1007/s00261-016-0855-z. PMID: 27663437
Rohatgi S, Howard SA, Tirumani SH, Ramaiya NH, Krajewski KM
Can Assoc Radiol J 2015 May;66(2):121-9. Epub 2015 Feb 3 doi: 10.1016/j.carj.2014.11.001. PMID: 25660299
Brown DF
Emerg Med Clin North Am 2001 Nov;19(4):913-23, vi. doi: 10.1016/s0733-8627(05)70226-1. PMID: 11762279

Therapy

Bejjani A, Khairani CD, Assi A, Piazza G, Sadeghipour P, Talasaz AH, Fanikos J, Connors JM, Siegal DM, Barnes GD, Martin KA, Angiolillo DJ, Kleindorfer D, Monreal M, Jimenez D, Middeldorp S, Elkind MSV, Ruff CT, Goldhaber SZ, Krumholz HM, Mehran R, Cushman M, Eikelboom JW, Lip GYH, Weitz JI, Lopes RD, Bikdeli B
J Am Coll Cardiol 2024 Jan 23;83(3):444-465. doi: 10.1016/j.jacc.2023.10.038. PMID: 38233019
Vedantham S
Hematology Am Soc Hematol Educ Program 2017 Dec 8;2017(1):681-685. doi: 10.1182/asheducation-2017.1.681. PMID: 29222321Free PMC Article
Bader KB, Bouchoux G, Holland CK
Adv Exp Med Biol 2016;880:339-62. doi: 10.1007/978-3-319-22536-4_19. PMID: 26486347Free PMC Article
Sanford M, Plosker GL
Drugs 2008;68(12):1699-709. doi: 10.2165/00003495-200868120-00007. PMID: 18681492
Lee MS, Singh V, Wilentz JR, Makkar RR
J Invasive Cardiol 2004 Oct;16(10):587-91. PMID: 15505358

Prognosis

Simard TJ, Hibbert B, Alkhouli MA, Abraham NS, Holmes DR Jr
EuroIntervention 2022 Jun 24;18(3):224-232. doi: 10.4244/EIJ-D-21-01010. PMID: 35440430
Fender EA, Kiani JG, Holmes DR Jr
Curr Atheroscler Rep 2016 Nov;18(11):65. doi: 10.1007/s11883-016-0616-z. PMID: 27696317
Leppert M, Poisson SN, Carroll JD
Cardiol Clin 2016 May;34(2):225-30. Epub 2016 Mar 9 doi: 10.1016/j.ccl.2015.12.004. PMID: 27150170
Wagener JF, Rao SV
Curr Atheroscler Rep 2015 Mar;17(3):489. doi: 10.1007/s11883-015-0489-6. PMID: 25651786
Targarona EM
Surg Innov 2008 Dec;15(4):266-70. doi: 10.1177/1553350608324931. PMID: 19036731

Clinical prediction guides

Patel M, Wei X, Weigel K, Gertz ZM, Kron J, Robinson AA, Trankle CR
J Cardiovasc Pharmacol 2021 Sep 1;78(3):361-371. doi: 10.1097/FJC.0000000000001064. PMID: 34074905
Seners P, Ben Hassen W, Lapergue B, Arquizan C, Heldner MR, Henon H, Perrin C, Strambo D, Cottier JP, Sablot D, Girard Buttaz I, Tamazyan R, Preterre C, Agius P, Laksiri N, Mechtouff L, Béjot Y, Duong DL, Mounier-Vehier F, Mione G, Rosso C, Lucas L, Papassin J, Aignatoaie A, Triquenot A, Carrera E, Niclot P, Obadia A, Lyoubi A, Garnier P, Crainic N, Wolff V, Tracol C, Philippeau F, Lamy C, Soize S, Baron JC, Turc G; MINOR-STROKE Collaborators
JAMA Neurol 2021 Mar 1;78(3):321-328. doi: 10.1001/jamaneurol.2020.4557. PMID: 33427887Free PMC Article
Habash F, Vallurupalli S
Ther Adv Cardiovasc Dis 2017 Aug;11(8):203-213. Epub 2017 Jun 7 doi: 10.1177/1753944717711139. PMID: 28589748Free PMC Article
Santos PM, López EB, Barrio EE, Marrupe LH, Valtierra JJ, González FP, de la Rosa Riestra A, Ruiz RC, Rodríguez JB
Int J Cardiovasc Imaging 2014 Jan;30(1):67. Epub 2013 Oct 10 doi: 10.1007/s10554-013-0299-2. PMID: 24113896
Buckley O, Rybicki FJ, Gerson DS, Huether C, Prior RF, Powers SL, Ersoy H
Int J Cardiovasc Imaging 2010 Jan;26(1):65-76. Epub 2009 Sep 24 doi: 10.1007/s10554-009-9504-8. PMID: 19777368

Recent systematic reviews

Azzam AY, Mortezaei A, Morsy MM, Essibayi MA, Ghozy S, Elamin O, Azab MA, Elswedy A, Altschul D, Kadirvel R, Brinjikji W, Kallmes DF
J Neurol Sci 2024 Apr 15;459:122948. Epub 2024 Mar 5 doi: 10.1016/j.jns.2024.122948. PMID: 38457956
Di Nisio M, Wichers IM, Middeldorp S
Cochrane Database Syst Rev 2018 Feb 25;2(2):CD004982. doi: 10.1002/14651858.CD004982.pub6. PMID: 29478266Free PMC Article
Schultz J, Andersen A, Kabrhel C, Nielsen-Kudsk JE
EuroIntervention 2018 Feb 20;13(14):1721-1727. doi: 10.4244/EIJ-D-17-00437. PMID: 29175770
Fields JM, Davis J, Girson L, Au A, Potts J, Morgan CJ, Vetter I, Riesenberg LA
J Am Soc Echocardiogr 2017 Jul;30(7):714-723.e4. Epub 2017 May 9 doi: 10.1016/j.echo.2017.03.004. PMID: 28495379
Barrera LM, Perel P, Ker K, Cirocchi R, Farinella E, Morales Uribe CH
Cochrane Database Syst Rev 2013 Mar 28;(3):CD008303. doi: 10.1002/14651858.CD008303.pub2. PMID: 23543562

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