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Unresectable Triple-Negative Breast Carcinoma

MedGen UID:
1718900
Concept ID:
C5237219
Neoplastic Process

Definition

Triple-negative breast carcinoma that is not amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Triple-Negative Breast Carcinoma

Professional guidelines

PubMed

Haiderali A, Huang M, Pan W, Akers KG, Maciel D, Frederickson AM
Future Oncol 2024;20(22):1587-1600. Epub 2024 Apr 10 doi: 10.2217/fon-2023-0301. PMID: 38597713Free PMC Article
Pérez-García J, Soberino J, Racca F, Gion M, Stradella A, Cortés J
Expert Opin Biol Ther 2020 Sep;20(9):981-989. Epub 2020 May 25 doi: 10.1080/14712598.2020.1769063. PMID: 32450725
Reddy SM, Carroll E, Nanda R
Expert Rev Anticancer Ther 2020 Mar;20(3):151-158. Epub 2020 Feb 27 doi: 10.1080/14737140.2020.1732211. PMID: 32067545

Recent clinical studies

Etiology

Loap P, Loirat D, Berger F, Rodrigues M, Bazire L, Pierga JY, Vincent-Salomon A, Laki F, Boudali L, Raizonville L, Mosseri V, Jochem A, Eeckhoutte A, Diallo M, Stern MH, Fourquet A, Kirova Y
JAMA Oncol 2022 Dec 1;8(12):1802-1808. doi: 10.1001/jamaoncol.2022.5074. PMID: 36301572Free PMC Article
Latif F, Bint Abdul Jabbar H, Malik H, Sadaf H, Sarfraz A, Sarfraz Z, Cherrez-Ojeda I
Expert Rev Anticancer Ther 2022 Feb;22(2):229-235. Epub 2022 Jan 24 doi: 10.1080/14737140.2022.2023011. PMID: 34949142
Pérez-García J, Soberino J, Racca F, Gion M, Stradella A, Cortés J
Expert Opin Biol Ther 2020 Sep;20(9):981-989. Epub 2020 May 25 doi: 10.1080/14712598.2020.1769063. PMID: 32450725
Schmid P, Rugo HS, Adams S, Schneeweiss A, Barrios CH, Iwata H, Diéras V, Henschel V, Molinero L, Chui SY, Maiya V, Husain A, Winer EP, Loi S, Emens LA; IMpassion130 Investigators
Lancet Oncol 2020 Jan;21(1):44-59. Epub 2019 Nov 27 doi: 10.1016/S1470-2045(19)30689-8. PMID: 31786121
Schmid P, Adams S, Rugo HS, Schneeweiss A, Barrios CH, Iwata H, Diéras V, Hegg R, Im SA, Shaw Wright G, Henschel V, Molinero L, Chui SY, Funke R, Husain A, Winer EP, Loi S, Emens LA; IMpassion130 Trial Investigators
N Engl J Med 2018 Nov 29;379(22):2108-2121. Epub 2018 Oct 20 doi: 10.1056/NEJMoa1809615. PMID: 30345906

Diagnosis

Manna M, Brabant M, Greene R, Chamberlain MD, Kumar A, Alimohamed N, Brezden-Masley C
Curr Oncol 2024 Sep 21;31(9):5694-5708. doi: 10.3390/curroncol31090422. PMID: 39330050Free PMC Article
Fusco N, Ivanova M, Frascarelli C, Criscitiello C, Cerbelli B, Pignataro MG, Pernazza A, Sajjadi E, Venetis K, Cursano G, Pagni F, Di Bella C, Accardo M, Amato M, Amico P, Bartoli C, Bogina G, Bortesi L, Boldorini R, Bruno S, Cabibi D, Caruana P, Dainese E, De Camilli E, Dell'Anna V, Duda L, Emmanuele C, Fanelli GN, Fernandes B, Ferrara G, Gnetti L, Gurrera A, Leone G, Lucci R, Mancini C, Marangi G, Mastropasqua MG, Nibid L, Orrù S, Pastena M, Peresi M, Perracchio L, Santoro A, Vezzosi V, Zambelli C, Zuccalà V, Rizzo A, Costarelli L, Pietribiasi F, Santinelli A, Scatena C, Curigliano G, Guerini-Rocco E, Martini M, Graziano P, Castellano I, d'Amati G
Crit Rev Oncol Hematol 2023 Oct;190:104103. Epub 2023 Aug 16 doi: 10.1016/j.critrevonc.2023.104103. PMID: 37595344
Loap P, Loirat D, Berger F, Rodrigues M, Bazire L, Pierga JY, Vincent-Salomon A, Laki F, Boudali L, Raizonville L, Mosseri V, Jochem A, Eeckhoutte A, Diallo M, Stern MH, Fourquet A, Kirova Y
JAMA Oncol 2022 Dec 1;8(12):1802-1808. doi: 10.1001/jamaoncol.2022.5074. PMID: 36301572Free PMC Article
Pérez-García J, Soberino J, Racca F, Gion M, Stradella A, Cortés J
Expert Opin Biol Ther 2020 Sep;20(9):981-989. Epub 2020 May 25 doi: 10.1080/14712598.2020.1769063. PMID: 32450725
Reddy SM, Carroll E, Nanda R
Expert Rev Anticancer Ther 2020 Mar;20(3):151-158. Epub 2020 Feb 27 doi: 10.1080/14737140.2020.1732211. PMID: 32067545

Therapy

Dri A, Arpino G, Bianchini G, Curigliano G, Danesi R, De Laurentiis M, Del Mastro L, Fabi A, Generali D, Gennari A, Guarneri V, Santini D, Simoncini E, Zamagni C, Puglisi F
Cancer Treat Rev 2024 Feb;123:102672. Epub 2023 Dec 14 doi: 10.1016/j.ctrv.2023.102672. PMID: 38118302
Latif F, Bint Abdul Jabbar H, Malik H, Sadaf H, Sarfraz A, Sarfraz Z, Cherrez-Ojeda I
Expert Rev Anticancer Ther 2022 Feb;22(2):229-235. Epub 2022 Jan 24 doi: 10.1080/14737140.2022.2023011. PMID: 34949142
Miles D, Gligorov J, André F, Cameron D, Schneeweiss A, Barrios C, Xu B, Wardley A, Kaen D, Andrade L, Semiglazov V, Reinisch M, Patel S, Patre M, Morales L, Patel SL, Kaul M, Barata T, O'Shaughnessy J; IMpassion131 investigators
Ann Oncol 2021 Aug;32(8):994-1004. Epub 2021 Jul 1 doi: 10.1016/j.annonc.2021.05.801. PMID: 34219000
Kwapisz D
Cancer Immunol Immunother 2021 Mar;70(3):607-617. Epub 2020 Oct 5 doi: 10.1007/s00262-020-02736-z. PMID: 33015734Free PMC Article
Schmid P, Adams S, Rugo HS, Schneeweiss A, Barrios CH, Iwata H, Diéras V, Hegg R, Im SA, Shaw Wright G, Henschel V, Molinero L, Chui SY, Funke R, Husain A, Winer EP, Loi S, Emens LA; IMpassion130 Trial Investigators
N Engl J Med 2018 Nov 29;379(22):2108-2121. Epub 2018 Oct 20 doi: 10.1056/NEJMoa1809615. PMID: 30345906

Prognosis

Dent R, André F, Gonçalves A, Martin M, Schmid P, Schütz F, Kümmel S, Swain SM, Bilici A, Loirat D, Villalobos Valencia R, Im SA, Park YH, De Laurentis M, Colleoni M, Guarneri V, Bianchini G, Li H, Kirchmayer Machackova Z, Mouta J, Deurloo R, Gan X, Fan M, Mani A, Swat A, Cortés J
Ann Oncol 2024 Jul;35(7):630-642. Epub 2024 May 15 doi: 10.1016/j.annonc.2024.04.001. PMID: 38755096
Heeke AL, Tan AR
Cancer Metastasis Rev 2021 Jun;40(2):537-547. Epub 2021 Jun 8 doi: 10.1007/s10555-021-09972-4. PMID: 34101053Free PMC Article
Kwapisz D
Cancer Immunol Immunother 2021 Mar;70(3):607-617. Epub 2020 Oct 5 doi: 10.1007/s00262-020-02736-z. PMID: 33015734Free PMC Article
Tufano AM, Teplinsky E, Landry CA
Clin Breast Cancer 2021 Feb;21(1):1-9. Epub 2020 Jul 3 doi: 10.1016/j.clbc.2020.07.001. PMID: 32800492
Schmid P, Rugo HS, Adams S, Schneeweiss A, Barrios CH, Iwata H, Diéras V, Henschel V, Molinero L, Chui SY, Maiya V, Husain A, Winer EP, Loi S, Emens LA; IMpassion130 Investigators
Lancet Oncol 2020 Jan;21(1):44-59. Epub 2019 Nov 27 doi: 10.1016/S1470-2045(19)30689-8. PMID: 31786121

Clinical prediction guides

Loap P, Loirat D, Berger F, Rodrigues M, Bazire L, Pierga JY, Vincent-Salomon A, Laki F, Boudali L, Raizonville L, Mosseri V, Jochem A, Eeckhoutte A, Diallo M, Stern MH, Fourquet A, Kirova Y
JAMA Oncol 2022 Dec 1;8(12):1802-1808. doi: 10.1001/jamaoncol.2022.5074. PMID: 36301572Free PMC Article
Emens LA, Adams S, Barrios CH, Diéras V, Iwata H, Loi S, Rugo HS, Schneeweiss A, Winer EP, Patel S, Henschel V, Swat A, Kaul M, Molinero L, Patel S, Chui SY, Schmid P
Ann Oncol 2021 Aug;32(8):983-993. Epub 2021 Jul 1 doi: 10.1016/j.annonc.2021.05.355. PMID: 34272041
Heeke AL, Tan AR
Cancer Metastasis Rev 2021 Jun;40(2):537-547. Epub 2021 Jun 8 doi: 10.1007/s10555-021-09972-4. PMID: 34101053Free PMC Article
Emens LA, Molinero L, Loi S, Rugo HS, Schneeweiss A, Diéras V, Iwata H, Barrios CH, Nechaeva M, Nguyen-Duc A, Chui SY, Husain A, Winer EP, Adams S, Schmid P
J Natl Cancer Inst 2021 Aug 2;113(8):1005-1016. doi: 10.1093/jnci/djab004. PMID: 33523233Free PMC Article
Tufano AM, Teplinsky E, Landry CA
Clin Breast Cancer 2021 Feb;21(1):1-9. Epub 2020 Jul 3 doi: 10.1016/j.clbc.2020.07.001. PMID: 32800492

Recent systematic reviews

Haiderali A, Huang M, Pan W, Akers KG, Maciel D, Frederickson AM
Future Oncol 2024;20(22):1587-1600. Epub 2024 Apr 10 doi: 10.2217/fon-2023-0301. PMID: 38597713Free PMC Article

Supplemental Content

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