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Actin-binding FH2 (formin homology 2) family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 818984, updated on 19-Feb-2025

Summary

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Official Full Name
Actin-binding FH2 (formin homology 2) family protein
Primary source
TAIR:AT2G43800
Locus tag
AT2G43800
See related
Araport:AT2G43800
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F18O19.9
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Genomic context

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Location:
chromosome: 2
Exon count:
4
Sequence:
Chromosome: 2; NC_003071.7 (18145439..18149031)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene MAP kinase 6 Neighboring gene corepressor Neighboring gene Small nuclear ribonucleoprotein family protein Neighboring gene UDP-glucosyltransferase 74F2 Neighboring gene miscRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis formin 2 regulates cell-to-cell trafficking by capping and stabilizing actin filaments at plasmodesmata. Diao M, et al. Elife, 2018 Aug 16. PMID 30113309, Free PMC Article
  2. Formin homology 2 domains occur in multiple contexts in angiosperms. Cvrcková F, et al. BMC Genomics, 2004 Jul 15. PMID 15256004, Free PMC Article
  3. Formins: intermediates in signal-transduction cascades that affect cytoskeletal reorganization. Deeks MJ, et al. Trends Plant Sci, 2002 Nov. PMID 12417149
  4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

General gene information

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NM_129942.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables actin binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within barbed-end actin filament capping IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within plasmodesmata-mediated intercellular transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
colocalizes_with plasmodesma IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Actin-binding FH2 (formin homology 2) family protein
NP_181908.1
  • Actin-binding FH2 (formin homology 2) family protein; FUNCTIONS IN: actin binding; INVOLVED IN: cellular component organization, actin cytoskeleton organization; LOCATED IN: plasma membrane; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Actin-binding FH2/DRF autoregulatory (InterPro:IPR003104), Actin-binding FH2 (InterPro:IPR015425); BEST Arabidopsis thaliana protein match is: formin homology 1 (TAIR:AT3G25500.1); Has 24262 Blast hits to 14906 proteins in 847 species: Archae - 39; Bacteria - 2066; Metazoa - 8621; Fungi - 3513; Plants - 5949; Viruses - 1021; Other Eukaryotes - 3053 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    18145439..18149031
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_129942.3 → NP_181908.1  Actin-binding FH2 (formin homology 2) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_181908.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O22824
    UniProtKB/TrEMBL
    A0A178VS83, A0A5S9X7A1
    Conserved Domains (1) summary
    pfam02181
    Location:438 → 839
    FH2; Formin Homology 2 Domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O22824.1

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