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LOC127894877 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:45184575-45185320 [ Homo sapiens (human) ]

Gene ID: 127894877, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127894877
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:45184575-45185320
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127894877 in Genome Data Viewer
Location:
chromosome: 21
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (43764694..43765439)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (42120304..42121049)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (45184575..45185320)

Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124905032 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18546 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13364 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13365 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:45139703-45140612 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18547 Neighboring gene pyridoxal kinase Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:45146555-45147396 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:45148239-45149080 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:45149081-45149922 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45151396-45151896 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45152891-45153850 Neighboring gene uncharacterized LOC105372824 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45157073-45157572 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:45159504-45160242 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:45160243-45160981 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:45183829-45184574 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:45186633-45187246 Neighboring gene PDXK-CSTB intergenic CAGE-defined low expression enhancer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45189831-45190753 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45190754-45191675 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13368 Neighboring gene cystatin B upstream repeat instability region Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45198401-45199200 Neighboring gene uncharacterized LOC105372825 Neighboring gene cystatin B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_144512.1 

    Range
    101..846
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

    Range
    43764694..43765439
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060945.1 Alternate T2T-CHM13v2.0

    Range
    42120304..42121049
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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