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LOC127886968 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:41779239-41780108 [ Homo sapiens (human) ]

Gene ID: 127886968, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127886968
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:41779239-41780108
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127886968 in Genome Data Viewer
Location:
chromosome: 17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (43701871..43702740)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (44554427..44555296)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (41779239..41780108)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:41729461-41729960 Neighboring gene mesenchyme homeobox 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:41738043-41738584 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:41743014-41743539 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:41745859-41746358 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:41746933-41747456 Neighboring gene long intergenic non-protein coding RNA 2594 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:41747457-41747978 Neighboring gene uncharacterized LOC107985085 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:41754903-41755667 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:41767960-41768460 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:41768461-41768961 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12248 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8562 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8563 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr17:41795928-41796532 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8564 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8565 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8566 Neighboring gene Wolf-Hirschhorn syndrome candidate 1-like 2, pseudogene Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:41811531-41812180 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:41821332-41821491 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:41831689-41831891 Neighboring gene sclerostin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_136650.1 

    Range
    101..970
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    43701871..43702740
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    44554427..44555296
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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