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LOC127884008 OCT4-NANOG hESC enhancer GRCh37_chr16:53861530-53862207 [ Homo sapiens (human) ]

Gene ID: 127884008, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127884008
Gene description
OCT4-NANOG hESC enhancer GRCh37_chr16:53861530-53862207
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127884008 in Genome Data Viewer
Location:
chromosome: 16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (53827618..53828295)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (59625363..59626040)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (53861530..53862207)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene NANOG hESC enhancer GRCh37_chr16:53659615-53660133 Neighboring gene RPGRIP1 like Neighboring gene VISTA enhancer hs59 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7502 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:53737766-53738266 Neighboring gene uncharacterized LOC124903691 Neighboring gene FTO alpha-ketoglutarate dependent dioxygenase Neighboring gene Sharpr-MPRA regulatory region 10092 Neighboring gene VISTA enhancer hs155 Neighboring gene Sharpr-MPRA regulatory region 7594 Neighboring gene VISTA enhancer hs157 Neighboring gene VISTA enhancer hs156 Neighboring gene Sharpr-MPRA regulatory region 2551 Neighboring gene uncharacterized LOC105371271 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr16:54082723-54083657 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr16:54083658-54084591 Neighboring gene FTO intronic transcript 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_133907.1 

    Range
    101..778
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    53827618..53828295
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    59625363..59626040
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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