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LOC127820194 H3K4me1 hESC enhancer GRCh37_chr11:2818029-2818530 [ Homo sapiens (human) ]

Gene ID: 127820194, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127820194
Gene description
H3K4me1 hESC enhancer GRCh37_chr11:2818029-2818530
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127820194 in Genome Data Viewer
Location:
chromosome: 11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (2796799..2797300)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (2886155..2886656)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (2818029..2818530)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene potassium voltage-gated channel subfamily Q member 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3071 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4306 Neighboring gene KCNQ1 opposite strand/antisense transcript 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:2706658-2707620 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:2709545-2710505 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:2714101-2714968 Neighboring gene nonconserved acetylation island sequence 52 enhancer Neighboring gene ReSE screen-validated silencer GRCh37_chr11:2729441-2729611 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:2735134-2735776 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:2739659-2740558 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr11:2741460-2742359 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:2744161-2745061 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:2745062-2745961 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:2746137-2747132 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_21090 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:2755915-2756416 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_21101 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:2759896-2760754 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:2762325-2762961 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:2791793-2792456 Neighboring gene uncharacterized LOC124902614 Neighboring gene cytochrome c oxidase subunit 6C pseudogene 18 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:2821032-2821969 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:2826269-2826768 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:2832501-2833263 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:2833264-2834027 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:2848795-2849695 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:2856199-2857066 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:2857067-2857933 Neighboring gene KCNQ1 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:2878979-2879960 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:2884189-2884886 Neighboring gene CRISPRi-validated cis-regulatory element chr11.592 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:2890154-2890662 Neighboring gene KCNQ1 downstream neighbor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_121659.1 

    Range
    101..602
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    2796799..2797300
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    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187585.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    28986..29487
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    2886155..2886656
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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