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LOC127819048 H3K4me1 hESC enhancer GRCh37_chr10:104260453-104260953 [ Homo sapiens (human) ]

Gene ID: 127819048, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127819048
Gene description
H3K4me1 hESC enhancer GRCh37_chr10:104260453-104260953
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127819048 in Genome Data Viewer
Location:
chromosome: 10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (102500696..102501196)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (103385683..103386183)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (104260453..104260953)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene C10orf95 antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2760 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2761 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:104211267-104211949 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:104214138-104214726 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:104214727-104215314 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr10:104215315-104215904 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr10:104215905-104216492 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:104216493-104217081 Neighboring gene chromosome 10 open reading frame 95 Neighboring gene uncharacterized LOC124902493 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3937 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:104220868-104221551 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:104221552-104222234 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:104233222-104233665 Neighboring gene major facilitator superfamily domain containing 13A Neighboring gene actin related protein 1A Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3938 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2763 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2764 Neighboring gene Sharpr-MPRA regulatory region 236 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:104264916-104265416 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3939 Neighboring gene SUFU negative regulator of hedgehog signaling Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3940 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:104325435-104326134 Neighboring gene ribosomal protein L23a pseudogene 58 Neighboring gene RNA, U6 small nuclear 43, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_120520.1 

    Range
    101..601
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    102500696..102501196
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    103385683..103386183
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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