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LOC127271261 H3K27ac hESC enhancer GRCh37_chr1:204046628-204047556 [ Homo sapiens (human) ]

Gene ID: 127271261, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127271261
Gene description
H3K27ac hESC enhancer GRCh37_chr1:204046628-204047556
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive and primed human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127271261 in Genome Data Viewer
Location:
chromosome: 1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (204077500..204078428)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (203341642..203342570)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (204046628..204047556)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371689 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:203965665-203966228 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:203995579-203996128 Neighboring gene long intergenic non-protein coding RNA 303 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:204035195-204035714 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:204037795-204038296 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:204042922-204043614 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:204044309-204045000 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:204047557-204048485 Neighboring gene Sharpr-MPRA regulatory region 2526 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:204051273-204052200 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:204056259-204056803 Neighboring gene SRY-box transcription factor 13 Neighboring gene HNF4 motif-containing MPRA enhancer 209 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:204076334-204077177 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:204077178-204078020 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:204078021-204078864 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:204094655-204095156 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:204095157-204095656 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:204099007-204099510 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:204099511-204100013 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:204100030-204100566 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:204100567-204101102 Neighboring gene ethanolamine kinase 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:204120251-204120950 Neighboring gene estrogen receptor responsive lncRNA 1 Neighboring gene REN promoter and enhancer region Neighboring gene renin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_093113.1 

    Range
    101..1029
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    204077500..204078428
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    203341642..203342570
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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