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LOC127268911 H3K4me1 hESC enhancer GRCh37_chr1:43436637-43437138 [ Homo sapiens (human) ]

Gene ID: 127268911, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127268911
Gene description
H3K4me1 hESC enhancer GRCh37_chr1:43436637-43437138
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127268911 in Genome Data Viewer
Location:
chromosome: 1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (42970966..42971467)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (42841436..42841937)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (43436637..43437138)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene ATPase H+ transporting V1 subunit E1 pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 899 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 900 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 901 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:43392725-43393224 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:43394256-43394898 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:43394899-43395539 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 902 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:43400317-43401109 Neighboring gene solute carrier family 2 member 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 903 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:43406478-43406986 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:43408512-43409020 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 906 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 907 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 908 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:43411987-43412488 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:43412489-43412988 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:43416007-43416542 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 909 Neighboring gene Sharpr-MPRA regulatory region 3978 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:43418797-43419741 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 910 Neighboring gene ATPase H+ transporting V0 subunit c pseudogene 4 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 772 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:43424712-43424895 Neighboring gene Sharpr-MPRA regulatory region 619 Neighboring gene SLC2A1 divergent transcript Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:43437139-43437638 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:43438752-43439252 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:43439253-43439753 Neighboring gene RNA, U6 small nuclear 880, pseudogene Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:43473322-43474029 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:43474030-43474738 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr1:43474739-43475446 Neighboring gene uncharacterized LOC124904715

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_090772.1 

    Range
    101..602
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    42970966..42971467
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    42841436..42841937
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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