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CYLD-AS1 CYLD antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 102724907, updated on 4-Mar-2025

Summary

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Official Symbol
CYLD-AS1provided by HGNC
Official Full Name
CYLD antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:55352
See related
Ensembl:ENSG00000261644 AllianceGenome:HGNC:55352
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in spleen (RPKM 2.0), appendix (RPKM 2.0) and 25 other tissues See more
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Genomic context

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See CYLD-AS1 in Genome Data Viewer
Location:
16q12.1
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (50727415..50742747, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (56525049..56540389, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (50761326..50776658, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene NKD inhibitor of WNT signaling pathway 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:50636563-50637271 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:50640404-50641180 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr16:50643815-50644780 Neighboring gene NKD1 antisense RNA 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:50654230-50654780 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:50654831-50655338 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:50658527-50659292 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:50659293-50660056 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10819 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:50677347-50677501 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:50680473-50680991 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:50688285-50688465 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:50699127-50699628 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10820 Neighboring gene uncharacterized LOC101927272 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10821 Neighboring gene sorting nexin 20 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7489 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10822 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10823 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10824 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10825 Neighboring gene Sharpr-MPRA regulatory region 14141 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7490 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:50743936-50744141 Neighboring gene nucleotide binding oligomerization domain containing 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10826 Neighboring gene Sharpr-MPRA regulatory region 1297 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10827 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7491 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10828 Neighboring gene microRNA 3181 Neighboring gene CYLD lysine 63 deubiquitinase Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7492 Neighboring gene CYLD antisense RNA 2 Neighboring gene long intergenic non-protein coding RNA 2168

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

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Related articles in PubMed

  1. Oxidative stress-induced lncRNA CYLD-AS1 promotes RPE inflammation via Nrf2/miR-134-5p/NF-κB signaling pathway. Du H, et al. FASEB J, 2022 Oct. PMID 36165267

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Oxidative stress-induced lncRNA CYLD-AS1 promotes RPE inflammation via Nrf2/miR-134-5p/NF-kappaB signaling pathway.
    Title: Oxidative stress-induced lncRNA CYLD-AS1 promotes RPE inflammation via Nrf2/miR-134-5p/NF-κB signaling pathway.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_184273.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007728

  2. NR_184274.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007728

  3. NR_184275.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007728

  4. NR_184276.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007728

  5. NR_184277.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007728

  6. NR_184278.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007728
    Related
    ENST00000563315.2

  7. NR_184279.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007728

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    50727415..50742747 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    56525049..56540389 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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