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. 2024 Jun 6;187(12):2897-2897.e1.
doi: 10.1016/j.cell.2024.05.009.

Resmetirom for treatment of MASH

Silvia Sookoian  1 , Carlos Jose Pirola  2
Affiliations

Resmetirom for treatment of MASH

Silvia Sookoian et al. Cell. .

Abstract

Resmetirom is an oral selective THR-β agonist conditionally approved for the treatment of patients with noncirrhotic MASH with moderate to advanced fibrosis. Resmetirom restores mitochondrial and hepatic metabolic function; reduces atherogenic lipids; improves hepatic steatosis, inflammation, and fibrosis; and has no significant effect on THR-α. To view this Bench to Bedside, open or download the PDF.

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