The Role of Genetics in Pancreatitis
- PMID: 30241646
- DOI: 10.1016/j.giec.2018.06.001
The Role of Genetics in Pancreatitis
Abstract
Individuals with acute recurrent and chronic pancreatitis may have an inherited predisposition to the development of the disease. Pancreatitis in the setting of a significant family history of the disease can be classified as hereditary or familial pancreatitis. In this article, the authors closely examine the specific genes implicated in pancreatitis, investigate the role of genetic testing for diagnosis, and describe the impact of genetic testing results on clinical management.
Keywords: CFTR; Familial pancreatitis; Genetic evaluation; Genetic variants associated with pancreatitis; Hereditary pancreatitis; PRSS1; SPINK1.
Copyright © 2018 Elsevier Inc. All rights reserved.
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