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Review

Coenzyme Q10

No authors listed
In: Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006.
.
Free Books & Documents
Review

Coenzyme Q10

No authors listed.
Free Books & Documents

Excerpt

Coenzyme Q10 (ubiquinone) is a normal part of the diet, and is also endogenously synthesized. It is a normal component of human milk, but milk levels are slightly low in the breastmilk of mothers with preterm infants. Coenzyme Q10 has no specific lactation-related uses and no data exist on the safety and efficacy of supplementation in nursing mothers or infants. Coenzyme Q10 supplements are usually well tolerated with only infrequent, minor side effects.

Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to prove the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does not certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed information about dietary supplements is available elsewhere on the LactMed Web site.

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References

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    1. Compagnoni G, Giuffre B, Lista G, et al. CoQ10 plasmatic levels in breast-fed infants compared to formula-fed infants. Biol Neonate. 2004;86:165–9. - PubMed
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    1. Todoroki Y, Tsukahara H, Ohshima Y, et al. Concentrations of thioredoxin, a redox-regulating protein, in umbilical cord blood and breast milk. Free Radic Res. 2005;39:291–7. - PubMed

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