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Review
. 2013 Aug 30;18(9):10465-83.
doi: 10.3390/molecules180910465.

Biological activities and phytochemicals of Swietenia macrophylla King

Soheil Zorofchian Moghadamtousi  1 , Bey Hing Goh, Chim Kei Chan, Tara Shabab, Habsah Abdul Kadir
Affiliations
Review

Biological activities and phytochemicals of Swietenia macrophylla King

Soheil Zorofchian Moghadamtousi et al. Molecules. .

Abstract

Swietenia macrophylla King (Meliaceae) is an endangered and medicinally important plant indigenous to tropical and subtropical regions of the World. S. macrophylla has been widely used in folk medicine to treat various diseases. The review reveals that limonoids and its derivatives are the major constituents of S. macrophylla. There are several data in the literature indicating a great variety of pharmacological activities of S. macrophylla, which exhibits antimicrobial, anti-inflammatory, antioxidant effects, antimutagenic, anticancer, antitumor and antidiabetic activities. Various other activities like anti-nociceptive, hypolipidemic, antidiarrhoeal, anti-infective, antiviral, antimalarial, acaricidal, antifeedant and heavy metal phytoremediation activity have also been reported. In view of the immense medicinal importance of S. macrophylla, this review aimed at compiling all currently available information on its ethnomedicinal uses, phytochemistry and biological activities of S. macrophylla, showing its importance.

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Figures

Figure 1
Figure 1
Chemical structures of various phytochemicals isolated from S. macrophylla.
See this image and copyright information in PMC

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