Case Reports
doi: 10.1002/ajmg.a.33840.
Epub 2011 Apr 11.
WNT10A and isolated hypodontia
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- PMID: 21484994
- DOI: 10.1002/ajmg.a.33840
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Case Reports
WNT10A and isolated hypodontia
Am J Med Genet A.
2011 May.
Abstract
WNT10A has been associated with various syndromes with ectodermal dysplasia from severe autosomal recessive SchO?pf-Schulz-Passarge syndrome to odonto-onycho-dermal dysplasia and autosomal dominant hypodontia. We report WNT10A mutations in an American family of which four members are affected with isolated hypodontia or microdontia. Here we demonstrate that in addition to MSX1, PAX9, AXIN2, and EDA, mutations in WNT10A can cause isolated hypodontia.
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