Randomized controlled trials: methodological concepts and critique
- PMID: 18385595
- DOI: 10.1097/01.NOR.0000315626.44137.94
Randomized controlled trials: methodological concepts and critique
Abstract
Randomized controlled trials, also known as true experiments or intervention studies, are considered to be the gold standard research design for demonstrating a cause-and-effect relationship between an intervention and an outcome. This article will describe key methodological concepts that make the randomized controlled trial this gold standard. Practicing from an evidence-based perspective requires practitioners to be able to critique the strengths and weaknesses of a research study in order to make decisions about adoption of the intervention into one's practice area. Key components to the critique of a randomized controlled trial are defined and the process is illustrated by a critique of Gallo and colleagues article, A Study of Naloxone Effect on Urinary Retention in the Patient Receiving Morphine PCA, published in this issue.
Comment on
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A study of naloxone effect on urinary retention in the patient receiving morphine patient-controlled analgesia.Orthop Nurs. 2008 Mar-Apr;27(2):111-5. doi: 10.1097/01.NOR.0000315625.44137.4f. Orthop Nurs. 2008. PMID: 18385594 Clinical Trial.
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