doi: 10.1016/j.neuron.2007.05.005.
The sodium "leak" has finally been plugged
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- PMID: 17521564
- DOI: 10.1016/j.neuron.2007.05.005
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The sodium "leak" has finally been plugged
Neuron.
.
Free article
Abstract
Most electrophysiologists generally do not speak highly of leak currents. In reality, these conductances represent a crucial functional mechanism by which neurons control resting membrane potentials. A new study in Cell by Lu et al. has surprisingly confirmed the identity of the long-sought voltage-insensitive sodium leak conductance to be encoded by the third branch of the voltage-gated sodium and calcium channel family.
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