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Case Reports
. 2006 Jan;34(1):55-9.
doi: 10.1016/j.pediatrneurol.2005.06.011.

Levetiracetam in a neonate with malignant migrating partial seizures

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Case Reports

Levetiracetam in a neonate with malignant migrating partial seizures

Ghassan Hmaimess et al. Pediatr Neurol. 2006 Jan.

Abstract

This report describes the first neonatal case of "malignant migrating partial seizures in infancy" with a positive therapeutic response to levetiracetam. This patient is the youngest reported infant with this rare syndrome, and the report provides the first documentation on levetiracetam treatment in a neonatal patient. Treatment with levetiracetam improved both ictal and interictal status. This observation also highlights the need to consider and include malignant migrating partial seizures in the differential diagnosis of early neonatal seizure disorders, even during the first hours of life.

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