Case Reports
doi: 10.1212/01.WNL.0000158615.56071.E3.
Leukoencephalopathy with ataxia, hypodontia, and hypomyelination
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- PMID: 15851747
- DOI: 10.1212/01.WNL.0000158615.56071.E3
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Case Reports
Leukoencephalopathy with ataxia, hypodontia, and hypomyelination
Neurology.
.
Abstract
The authors describe four unrelated girls with a distinctive neurologic disorder with early-onset progressive ataxia and hypodontia with a characteristic pattern of delayed dentition. Cerebral MRI shows hypomyelinated white matter and cerebellar atrophy; 1H-MRS of white matter reveals a marked elevation of myo-inositol.
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