Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation
- PMID: 15231951
- DOI: 10.1542/peds.114.1.297
Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation
Erratum in
- Pediatrics. 2004 Oct;114(4):1138
Abstract
Jaundice occurs in most newborn infants. Most jaundice is benign, but because of the potential toxicity of bilirubin, newborn infants must be monitored to identify those who might develop severe hyperbilirubinemia and, in rare cases, acute bilirubin encephalopathy or kernicterus. The focus of this guideline is to reduce the incidence of severe hyperbilirubinemia and bilirubin encephalopathy while minimizing the risks of unintended harm such as maternal anxiety, decreased breastfeeding, and unnecessary costs or treatment. Although kernicterus should almost always be preventable, cases continue to occur. These guidelines provide a framework for the prevention and management of hyperbilirubinemia in newborn infants of 35 or more weeks of gestation. In every infant, we recommend that clinicians 1) promote and support successful breastfeeding; 2) perform a systematic assessment before discharge for the risk of severe hyperbilirubinemia; 3) provide early and focused follow-up based on the risk assessment; and 4) when indicated, treat newborns with phototherapy or exchange transfusion to prevent the development of severe hyperbilirubinemia and, possibly, bilirubin encephalopathy (kernicterus).
Comment in
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Closing the gap between guidelines and practice: ensuring safe and healthy beginnings.Pediatrics. 2004 Aug;114(2):494-6. doi: 10.1542/peds.114.2.494. Pediatrics. 2004. PMID: 15286239 No abstract available.
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Management of hyperbilirubinemia: quality of evidence and cost.Pediatrics. 2004 Oct;114(4):1086-8. doi: 10.1542/peds.2004-1753. Pediatrics. 2004. PMID: 15466110 No abstract available.
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Hyperbilirubinemia guidelines and unintended harms.Pediatrics. 2004 Oct;114(4):1134-5; author reply 1135-7. doi: 10.1542/peds.2004-1584. Pediatrics. 2004. PMID: 15466132 No abstract available.
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Hyperbilirubinemia guidelines in newborn infants.Pediatrics. 2005 Mar;115(3):824-5. doi: 10.1542/peds.2004-2442. Pediatrics. 2005. PMID: 15741399 No abstract available.
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Computerized decision-making assistance for managing neonatal hyperbilirubinemia.Pediatrics. 2006 Jan;117(1):262-3. doi: 10.1542/peds.2005-2267. Pediatrics. 2006. PMID: 16396898 No abstract available.
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Hyperbilirubinemia in the newborn infant > or =35 weeks' gestation: an update with clarifications.Pediatrics. 2009 Oct;124(4):1193-8. doi: 10.1542/peds.2009-0329. Epub 2009 Sep 28. Pediatrics. 2009. PMID: 19786452 Review. No abstract available.
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