doi: 10.1136/adc.2003.031187.
Early proximal tubular dysfunction in Lowe's syndrome
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- PMID: 15102646
- PMCID: PMC1719890
- DOI: 10.1136/adc.2003.031187
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Early proximal tubular dysfunction in Lowe's syndrome
Arch Dis Child.
2004 May.
Abstract
The early diagnosis of Lowe's syndrome can be difficult. Urinary excretion of retinol binding protein (RBP) and the lysosomal enzyme N-acetyl-glucosaminidase (NAG) were significantly increased in boys with Lowe's syndrome. Measurement of these urine parameters is recommended in suspected cases.
Figures
Urinary excretion of RBP and NAG in eight patients with Lowe's syndrome. Results are factored by urine creatinine to correct the variation in urinary concentration.
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