Review
A multiple sclerosis-like illness in a man harboring the mtDNA 14484 mutation
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Review
A multiple sclerosis-like illness in a man harboring the mtDNA 14484 mutation
J Neuroophthalmol.
1999 Mar.
Abstract
In most cases of Leber's hereditary optic neuropathy (LHON) the only clinical manifestation is visual loss. A multiple sclerosis-like illness has been infrequently reported in association with LHON. Most patients are women harboring the mtDNA 11778 mutation. We present a young man with clinical and paraclinical evidence of a demyelinating process with profound bilateral visual loss who harbored the mtDNA 14484 mutation associated with LHON.
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