Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1999 Apr;80(4):339-42.
doi: 10.1136/adc.80.4.339.

Growth in Sotos syndrome

J C Agwu  1 , N J Shaw, J Kirk, S Chapman, D Ravine, T R Cole
Affiliations

Growth in Sotos syndrome

J C Agwu et al. Arch Dis Child. 1999 Apr.

Abstract

Although there are several reports on infant and childhood growth in patients with Sotos syndrome, there is little information on the final height achieved and puberty. Growth data on 40 patients (20 female and 20 male) aged 2-31 years were collected. These showed that patients with Sotos syndrome are excessively tall at birth, during infancy, and during childhood. Disproportionately long limbs constitute much of the increase in stature. However, the combination of advanced bone age and early onset of menarche led to a mean (SD) final height of 172.9 (5.7) cm in women. This is within the normal range for the population. Most of the men also attained a final height (mean, 184.3 cm; SD, 6.0) within the normal range, although exceptions were more likely in men than in women. Therefore, these results show that most patients with Sotos syndrome do not require intervention to limit their adult height.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Arch Dis Child. 1969 Apr;44(234):203-10 - PubMed
    1. J Pediatr. 1967 Jun;70(6):900-14 - PubMed
    1. J Pediatr. 1980 Apr;96(4):685-7 - PubMed
    1. Arch Dis Child. 1983 Oct;58(10):767-76 - PubMed
    1. Am J Med Genet. 1978;2(2):201-5 - PubMed