{"id":13285,"date":"2024-05-21T12:28:47","date_gmt":"2024-05-21T16:28:47","guid":{"rendered":"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/?p=13285"},"modified":"2024-05-21T12:28:47","modified_gmt":"2024-05-21T16:28:47","slug":"ortholog-groups-2-million-insect-genes","status":"publish","type":"post","link":"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2024\/05\/21\/ortholog-groups-2-million-insect-genes\/","title":{"rendered":"Ortholog Groups Added for ~2 Million Insect Genes"},"content":{"rendered":"

F<\/span>ind evolutiona<\/span>rily related genes across<\/span> insects and other<\/span> arthropods<\/span> on our new <\/span>Ortholog webpages<\/span><\/em><\/h4>\n

NCBI recently released a set of orthologs for approximately 2 million insect genes. You can now find and access the orthologous genes, transcripts, and proteins by searching a species and gene name in <\/span>NCBI All Databases<\/span><\/a>, <\/span>NCBI Gene<\/span><\/a>, or <\/span>NCBI Datasets<\/span><\/a>. As <\/span>previously described<\/span><\/a>, these orthologs are based on comparisons to the <\/span>Drosophila melanogaster <\/span><\/i>annotated genome. Using <\/span>Drosophila<\/span><\/i> gene nomenclature for orthologs should lead to more informative gene symbols for insects and other arthropods.<\/span>\u00a0<\/span><\/p>\n

Example: Getting insect orthologs for the Delta gene<\/h5>\n

\"Screenshots<\/p>\n

Figure 1: Three ways to access orthologs for a gene: <\/span>from the <\/span>information box on <\/span>an<\/span> <\/span>All Databases <\/span>S<\/span>earch<\/span><\/span><\/a> on the NCBI Homepage, <\/span>from a <\/span><\/span>Gene record page<\/span><\/span><\/a>, <\/span>and from the <\/span><\/span>Datasets Gene service<\/span><\/span><\/a>.<\/span><\/span>\u00a0<\/span><\/em><\/p>\n

\"Screenshot<\/p>\n

Figure 2: The orthologs page for the Delta gene filtered for members from the insect suborder <\/em>Apocrita (wasps, ants, and bees).\u00a0<\/em>\u00a0<\/span>\u00a0<\/span><\/p>\n

Command-line access<\/h4>\n

Use NCBI Datasets command line (CLI) tool for programmatic access to orthologs. <\/span>Download and install client<\/span><\/a>. See our <\/span>how-to-guide<\/span><\/a> to get started.\u00a0<\/span>\u00a0<\/span><\/p>\n

Currently accessing Orthologs through the NCBI FTP site?<\/h5>\n

All information is now integrated in the <\/span>gene_orthologs.gz<\/span><\/a> file. <\/span>\u00a0<\/span><\/p>\n

Learn more<\/h5>\n

For more information about\u202fNCBI Datasets\u202fand for step-by-step instructions on how to use it, see our <\/span>help documentation<\/span><\/a>.\u202f<\/span>\u00a0<\/span><\/p>\n

Stay up to date<\/h5>\n

NCBI Orthologs and NCBI Datasets are part of the <\/span>NIH Comparative Genomics Resource (CGR)<\/span><\/a>. CGR facilitates reliable comparative genomics analyses\u202ffor all eukaryotic organisms through an NCBI Toolkit and community collaboration.\u00a0<\/span>\u00a0<\/span><\/p>\n

Follow us on social\u202f<\/span>@NCBI<\/span><\/a> and join our <\/span>mailing list<\/span><\/a> to keep up to date with NCBI Datasets and other CGR news.<\/span>\u00a0<\/span><\/p>\n

Questions?<\/h5>\n

If you have questions or would like to provide feedback, please reach out to us at\u202finfo@ncbi.nlm.nih.gov<\/a>.\u202f<\/span>\u00a0<\/span><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Find evolutionarily related genes across insects and other arthropods on our new Ortholog webpages NCBI recently released a set of orthologs for approximately 2 million insect genes. You can now find and access the orthologous genes, transcripts, and proteins by searching a species and gene name in NCBI All Databases, NCBI Gene, or NCBI Datasets. … Continue reading Ortholog Groups Added for ~2 Million Insect Genes<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":42204617,"featured_media":13294,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"Ortholog Groups Added for ~2 Million Insect Genes","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[2248],"tags":[693060768,9714,693060836],"table_tags":[],"class_list":["post-13285","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-whats-new","tag-comparative-genomics-resource-cgr","tag-gene","tag-ncbi-datasets"],"jetpack_publicize_connections":[],"yoast_head":"\nOrtholog Groups Added for ~2 Million Insect Genes - NCBI Insights<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2024\/05\/21\/ortholog-groups-2-million-insect-genes\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ortholog Groups Added for ~2 Million Insect Genes - NCBI Insights\" \/>\n<meta property=\"og:description\" content=\"Find evolutionarily related genes across insects and other arthropods on our new Ortholog webpages NCBI recently released a set of orthologs for approximately 2 million insect genes. 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